Rabbit anti-Human, Mouse RPL23 Polyclonal Antibody | anti-RPL23 antibody

RPL23, ID (RPL23, 60S ribosomal protein L23, 60S ribosomal protein L17) (Biotin)

Cat. Num. AAA6343426

• Gene Names: RPL23; L23; rpL17
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry, ELISA
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: RPL23; Polyclonal Antibody; ID (RPL23; 60S ribosomal protein L23; 60S ribosomal protein L17) (Biotin); 60S ribosomal protein L17; anti-RPL23 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human RPL23. Species Crossreactivity: mouse
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-RPL23 antibody: Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 49-78 in the central region of human RPL23, UniProt Accession #NP_000969.1. Species sequence homology: bovine, zebrafish, porcine and rat
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of MBS642559 in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates that MBS642559 detected the RPL23 protein (arrow).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of MBS642559 in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS642559 for immunohistochemistry.)

Related Product Information for anti-RPL23 antibody

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Product Categories/Family for anti-RPL23 antibody

Antibodies; Ribosomal Proteins

References

1. Gehring, N.H., et al. Cell 137(3):536-548(2009). 2. Wanzel, M., et al. Nat. Cell Biol. 10(9):1051-1061(2008). 3. Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005). 4. Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005). 5. Jin, A., et al. Mol. Cell. Biol. 24(17):7669-7680(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 4506605
• NCBI GeneID: 9349
• NCBI Accession #: NP_000969.1
• NCBI GenBank Nucleotide #: NM_000978.3
• UniProt Accession #: P62829; P23131; P24048; Q29246; Q3SWV7; Q6P5S1
• Molecular Weight: 14,865 Da
• NCBI Official Full Name: 60S ribosomal protein L23
• NCBI Official Synonym Full Names: ribosomal protein L23
• NCBI Official Symbol: RPL23
• NCBI Official Synonym Symbols: L23; rpL17
• NCBI Protein Information: 60S ribosomal protein L23; ribosomal protein L17; 60S ribosomal protein L17
• UniProt Protein Name: 60S ribosomal protein L23
• Protein Family: 50S ribosomal protein
• UniProt Gene Name: RPL23
• UniProt Entry Name: RL23_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Uniprot Description

RPL23: a ribosomal protein of the L14P family. Located in the cytoplasm. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 60S subunit.

Protein type: Translation; Ribosomal

Chromosomal Location of Human Ortholog: 17q

Cellular Component: focal adhesion; membrane; cytoplasm; nucleolus; ribosome; cytosol

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: SRP-dependent cotranslational protein targeting to membrane; ribosomal protein import into nucleus; translational elongation; cellular protein metabolic process; viral reproduction; translation; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription; translational termination; viral infectious cycle