Rabbit anti-Human RPA43 Polyclonal Antibody | anti-TWISTNB antibody
RPA43 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of RPA43 Antibody (C-term) in Jurkat,K562 cell line lysates (35ug/lane).RPA43 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(RPA43 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RPA43 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Yuan, X., et al. EMBO Rep. 3(11):1082-1087(2002)
Kosan, C., et al. Cytogenet. Genome Res. 97 (3-4), 167-170 (2002)
NCBI and Uniprot Product Information
Uniprot Description
TWISTNB: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
Protein type: Nucleolus
Chromosomal Location of Human Ortholog: 7p21.1
Cellular Component: microtubule cytoskeleton; nucleoplasm; nucleolus; nucleus; DNA-directed RNA polymerase I complex
Biological Process: negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; gene expression; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; regulation of gene expression, epigenetic
Research Articles on TWISTNB
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Product Notes
The TWISTNB twistnb (Catalog #AAA9214729) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 298-326. The RPA43 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RPA43 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the TWISTNB twistnb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RPA43, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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