Western Blot (WB)
(Western blot analysis of RPA Interacting Protein in Jurkat cell lysate with RPA Interacting Protein antibody at (A) 1 and (B) 2 μg/mL. )
Rabbit RPA Interacting Protein Polyclonal Antibody | anti-RPAIN antibody
RPA Interacting Protein Antibody
Gene Names
RPAIN; RIP; HRIP
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
RPA Interacting Protein Antibody is affinity chromatography purified via peptide column.
Synonyms
RPA Interacting Protein; Polyclonal Antibody; RPA Interacting Protein Antibody; RIP; HRIP; RPA-interacting protein; hRIP; RPA interacting protein; anti-RPAIN antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
RPA Interacting Protein Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
219
Applicable Applications for anti-RPAIN antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
RPA Interacting Protein antibody can be used for detection of RPA Interacting Protein by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL.
Conjugate
Unconjugated
Immunogen
RPA IP antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human RPA IP.
Buffer
RPA Interacting Protein Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
RPA Interacting Protein antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of RPA Interacting Protein in Jurkat cell lysate with RPA Interacting Protein antibody at (A) 1 and (B) 2 μg/mL. )
Western Blot (WB)
(Western blot analysis of RPA Interacting Protein in Jurkat cell lysate with RPA Interacting Protein antibody at (A) 1 and (B) 2 μg/mL. )
Immunohistochemistry (IHC)
(Immunohistochemistry of RPA Interacting Protein in mouse stomach tissue with RPA Interacting Protein antibody at 2.5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of RPA Interacting Protein in mouse stomach tissue with RPA Interacting Protein antibody at 2.5 μg/mL.)
Related Product Information for anti-RPAIN antibody
RPA Interacting Protein Antibody: Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17,118 Da
NCBI Official Full Name
RPA interacting protein
NCBI Official Synonym Full Names
RPA interacting protein
NCBI Official Symbol
RPAIN
NCBI Official Synonym Symbols
RIP; HRIP
NCBI Protein Information
RPA-interacting protein; nuclear transporter; RAP interaction protein
UniProt Protein Name
RPA-interacting protein
Protein Family
UniProt Gene Name
RPAIN
UniProt Synonym Gene Names
RIP; hRIP
UniProt Entry Name
RIP_HUMAN
Uniprot Description
RPAIN: Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA repair, damage; DNA replication
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: PML body; cytoplasm; nucleolus; nucleus
Molecular Function: metal ion binding; protein complex binding
Biological Process: protein import into nucleus; DNA repair; DNA-dependent DNA replication; DNA recombination; response to UV
Research Articles on RPAIN
Similar Products
Product Notes
The RPAIN rpain (Catalog #AAA150791) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RPA Interacting Protein Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RPA Interacting Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). RPA Interacting Protein antibody can be used for detection of RPA Interacting Protein by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. Researchers should empirically determine the suitability of the RPAIN rpain for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RPA Interacting Protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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