Rabbit anti-Human RP9 Polyclonal Antibody | anti-RP9 antibody

RP9 Antibody - C-terminal region

Cat. Num. AAA3223280

• Gene Names: RP9; PAP1; PAP-1
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity purified
• Synonyms: RP9; Polyclonal Antibody; RP9 Antibody - C-terminal region; anti-RP9 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Affinity purified
• Form/Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Sequence: Synthetic peptide located within the following region: LKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKH
• Sequence Length: 221

• Applicable Applications for anti-RP9 antibody: Western Blot (WB)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RP9
• Preparation and Storage: For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Host: RabbitTarget Name: RP9Sample Tissue: Human MCF7 Whole Cell lysatesAntibody Dilution: 1ug/ml)

Related Product Information for anti-RP9 antibody

The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene.

Product Categories/Family for anti-RP9 antibody

Polyclonal; Cancer; RNA Binding Proteins; Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 42718020
• NCBI GeneID: 6100
• NCBI Accession #: NP_976033.1
• NCBI GenBank Nucleotide #: NM_203288.1
• UniProt Accession #: Q8TA86
• Molecular Weight: 24 kDa
• NCBI Official Full Name: retinitis pigmentosa 9 protein
• NCBI Official Synonym Full Names: RP9 pre-mRNA splicing factor
• NCBI Official Symbol: RP9
• NCBI Official Synonym Symbols: PAP1; PAP-1
• NCBI Protein Information: retinitis pigmentosa 9 protein
• UniProt Protein Name: Retinitis pigmentosa 9 protein
• Protein Family: Retinitis pigmentosa 9 protein
• UniProt Gene Name: RP9
• UniProt Synonym Gene Names: PAP-1
• UniProt Entry Name: RP9_HUMAN

NCBI Description

The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. [provided by RefSeq, Sep 2009]

Uniprot Description

RP9: Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1. Defects in RP9 are the cause of retinitis pigmentosa type 9 (RP9). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP9 inheritance is autosomal dominant.

Protein type: RNA processing

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: nucleoplasm; signal recognition particle receptor complex; cytoplasm; nucleus

Molecular Function: protein binding; zinc ion binding

Biological Process: RNA splicing; cognition

Disease: Retinitis Pigmentosa 9