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Western Blot (WB) (Western blot analysis of extracts of various cells, using RMI2 antibody.)

Rabbit anti-Human RMI2 Polyclonal Antibody | anti-RMI2 antibody

RMI2 Polyclonal Antibody

Gene Names
RMI2; BLAP18; C16orf75
Reactivity
Human
Applications
Western Blot
Purity
Antigen Affinity Purification
Synonyms
RMI2; Polyclonal Antibody; RMI2 Polyclonal Antibody; BLAP18; C16orf75; anti-RMI2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Sequence Length
147
Applicable Applications for anti-RMI2 antibody
Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
Recombinant protein of human RMI2
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cells, using RMI2 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cells, using RMI2 antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16kDa
NCBI Official Full Name
recQ-mediated genome instability protein 2
NCBI Official Synonym Full Names
RecQ mediated genome instability 2
NCBI Official Symbol
RMI2
NCBI Official Synonym Symbols
BLAP18; C16orf75
NCBI Protein Information
recQ-mediated genome instability protein 2
UniProt Protein Name
RecQ-mediated genome instability protein 2
UniProt Gene Name
RMI2
UniProt Synonym Gene Names
C16orf75; hRMI2; BLAP18
UniProt Entry Name
RMI2_HUMAN

NCBI Description

RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008]

Uniprot Description

RMI2: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress- induced nuclear foci and mitotic phosphorylation of BLM. Belongs to the RMI2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA replication

Chromosomal Location of Human Ortholog: 16p13.13

Cellular Component: cytoplasm; nucleoplasm; nucleus

Biological Process: DNA replication; DNA synthesis during DNA repair; strand displacement

Research Articles on RMI2

Similar Products

Product Notes

The RMI2 rmi2 (Catalog #AAA2541087) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RMI2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RMI2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the RMI2 rmi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RMI2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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