Human Pentraxin-3 ELISA Kit | PTX3 elisa kit

Pentraxin-3 (Human) OmniKine ELISA Kit

Cat. Num. AAA9502067

• Gene Names: PTX3; TSG-14; TNFAIP5
• Reactivity: Human
• Synonyms: Pentraxin-3; Pentraxin-3 (Human) OmniKine ELISA Kit; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14; TNFAIP5; TSG14; PTX3 elisa kit

• Reactivity: Human
• Specificity: The OmniKine Human Pentraxin-3 ELISA is capable of recognizing both recombinant and naturally produced Human Pentraxin-3 proteins. The antigens listed below were tested at 100 ng/ml and did not exhibit significant cross reactivity or interference.; Human: Pentraxin 3; Murine: Pentraxin 2, TSG; Rat: Pentraxin 2; The antigens listed below were tested at 35 ng/ml and exhibited less than 1.4% cross-reactivity.; Murine: Pentraxin 3
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 381

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 219-14000 pg/ml
• Sensitivity: 219-14000 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human Pentraxin-3 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Pentraxin-3 proteins within the range of 219-14000 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 167900484
• NCBI GeneID: 5806
• NCBI Accession #: NP_002843.2
• NCBI GenBank Nucleotide #: NM_002852.3
• UniProt Accession #: P26022; Q38M82; B2R6T6
• Molecular Weight: 41,976 Da
• NCBI Official Full Name: pentraxin-related protein PTX3
• NCBI Official Synonym Full Names: pentraxin 3
• NCBI Official Symbol: PTX3
• NCBI Official Synonym Symbols: TSG-14; TNFAIP5
• NCBI Protein Information: pentraxin-related protein PTX3
• UniProt Protein Name: Pentraxin-related protein PTX3
• Protein Family: Pentraxin-related protein
• UniProt Gene Name: PTX3
• UniProt Synonym Gene Names: TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14

NCBI Description

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]

Uniprot Description

PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q25.32

Cellular Component: extracellular region; extracellular space

Molecular Function: complement component C1q binding; identical protein binding; protein binding; virion binding; zymosan binding

Biological Process: inflammatory response; innate immune response; negative regulation of virion penetration into host cell; neutrophil degranulation; opsonization; positive regulation of nitric oxide biosynthetic process; positive regulation of phagocytosis; response to yeast