Western Blot (WB)
(Western blot analysis of Rkhd1 in MDA-MB-361 cell lysate with Rkhd1 antibody at (A) 1 ug/ml and (B) 2 ug/mL.)
Rabbit anti-Human Rkhd1 Polyclonal Antibody | anti-Rkhd1 antibody
Rkhd1 Antibody
Gene Names
MEX3D; MEX3; TINO; RKHD1; MEX-3D; RNF193; OK/SW-cl.4
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
Rkhd1; Polyclonal Antibody; Rkhd1 Antibody; RING finger and KH domain-containing protein 1; MEX3D; TINO; RING finger protein 193; RNF193; anti-Rkhd1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
666
Applicable Applications for anti-Rkhd1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide from near the center of human Rkhd1.
Target Name
Rkhd1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of Rkhd1 in MDA-MB-361 cell lysate with Rkhd1 antibody at (A) 1 ug/ml and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of Rkhd1 in MDA-MB-361 cell lysate with Rkhd1 antibody at (A) 1 ug/ml and (B) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of Rkhd1 in human small intestine tissue with Rkhd1 antibody at 2.5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of Rkhd1 in human small intestine tissue with Rkhd1 antibody at 2.5 ug/mL.)
Related Product Information for anti-Rkhd1 antibody
Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Product Categories/Family for anti-Rkhd1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,469 Da
NCBI Official Full Name
RNA-binding protein MEX3D isoform 2
NCBI Official Synonym Full Names
mex-3 RNA binding family member D
NCBI Official Symbol
MEX3D
NCBI Official Synonym Symbols
MEX3; TINO; RKHD1; MEX-3D; RNF193; OK/SW-cl.4
NCBI Protein Information
RNA-binding protein MEX3D
UniProt Protein Name
RNA-binding protein MEX3D
UniProt Gene Name
MEX3D
UniProt Synonym Gene Names
KIAA2031; RKHD1; RNF193
UniProt Entry Name
MEX3D_HUMAN
Uniprot Description
RKHD1: RNA binding protein, may be involved in post- transcriptional regulatory mechanisms. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: perinuclear region of cytoplasm; nucleus
Molecular Function: zinc ion binding; AU-rich element binding
Similar Products
Product Notes
The Rkhd1 mex3d (Catalog #AAA9410589) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rkhd1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Rkhd1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the Rkhd1 mex3d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rkhd1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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