Western Blot (WB)
(Western blot analysis of Rim3 in human brain tissue lysate with Rim3 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.)
Rabbit Rim3 Polyclonal Antibody | anti-RIMS3 antibody
Rim3, NT (Rab3-interacting molecule 3, regulating synaptic membrane exocytosis 3, RIM3 gamma, RIMS3, NIM3)
Gene Names
RIMS3; NIM3; RIM3
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Rim3; Polyclonal Antibody; NT (Rab3-interacting molecule 3; regulating synaptic membrane exocytosis 3; RIM3 gamma; RIMS3; NIM3); Anti -Rim3; anti-RIMS3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Rim3. Species crossreactivity: Mouse and rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-RIMS3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Elisa and Western Blot.
Dilution: Western Blot: 0.5-1ug/ml
Dilution: Western Blot: 0.5-1ug/ml
Immunogen
Synthetic peptide corresponding to 17aa from near the amino terminus of human Rim3 (GenBank accession no. NP_055562).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Western Blot (WB)
(Western blot analysis of Rim3 in human brain tissue lysate with Rim3 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of Rim3 in human brain tissue lysate with Rim3 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.)
Related Product Information for anti-RIMS3 antibody
Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neural transmission and plasticity (1,2). While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis (1). Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity (2). This antibody is predicted to have no cross-reactivity to other Rim proteins.
Product Categories/Family for anti-RIMS3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,796 Da
NCBI Official Full Name
regulating synaptic membrane exocytosis protein 3
NCBI Official Synonym Full Names
regulating synaptic membrane exocytosis 3
NCBI Official Symbol
RIMS3
NCBI Official Synonym Symbols
NIM3; RIM3
NCBI Protein Information
regulating synaptic membrane exocytosis protein 3; RIM 3; RIM3 gamma; Rab-3 interacting molecule 3; rab-3-interacting molecule 3
UniProt Protein Name
Regulating synaptic membrane exocytosis protein 3
Protein Family
UniProt Gene Name
RIMS3
UniProt Synonym Gene Names
KIAA0237; Nim3; RIM 3
UniProt Entry Name
RIMS3_HUMAN
Uniprot Description
RIMS3: Regulates synaptic membrane exocytosis.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 1p34.2
Cellular Component: presynaptic active zone; cell junction
Biological Process: regulation of membrane potential; neurotransmitter transport; calcium ion-dependent exocytosis
Research Articles on RIMS3
Similar Products
Product Notes
The RIMS3 rims3 (Catalog #AAA619429) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rim3, NT (Rab3-interacting molecule 3, regulating synaptic membrane exocytosis 3, RIM3 gamma, RIMS3, NIM3) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Rim3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Elisa and Western Blot. Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the RIMS3 rims3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rim3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
