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Immunohistochemistry (IHC) (Anti-RHOBTB2 / DBC2 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit anti-Mouse, Human RHOBTB2 / DBC2 Polyclonal Antibody | anti-RHOBTB2 / DBC2 antibody

Anti-RHOBTB2 / DBC2 Antibody (aa61-110) IHC-plus

Gene Names
RHOBTB2; DBC2
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
RHOBTB2 / DBC2; Polyclonal Antibody; Anti-RHOBTB2 / DBC2 Antibody (aa61-110) IHC-plus; Rabbit Polyclonal (IgG) to Human RHOBTB2 / DBC2; Human RHOBTB2 / DBC2; KIAA0717; p83; anti-RHOBTB2 / DBC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
RHBT2 Antibody detects endogenous levels of total RHBT2 protein.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
727
Applicable Applications for anti-RHOBTB2 / DBC2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:5000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)
Immunogen
RHOBTB2 / DBC2 antibody was raised against synthetic peptide from human RHBT2 (aa61-110).
Immunogen Description
Synthetic peptide from human RHBT2 (aa61-110).
Antigen Modification
aa61-110
Target Species
Human
Preparation and Storage
Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Anti-RHOBTB2 / DBC2 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-RHOBTB2 / DBC2 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of extracts from HepG2/HeLa cells, using RHBT2 Antibody. The lane on the right is treated with the synthesized peptide.)

Western Blot (WB) (Western blot of extracts from HepG2/HeLa cells, using RHBT2 Antibody. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-RHOBTB2 / DBC2 antibody
RHOBTB2 Antibody, DBC2 Antibody, KIAA0717 Antibody, p83 Antibody Description: The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
83,469 Da
NCBI Official Full Name
rho-related BTB domain-containing protein 2 isoform 3
NCBI Official Synonym Full Names
Rho-related BTB domain containing 2
NCBI Official Symbol
RHOBTB2
NCBI Official Synonym Symbols
DBC2
NCBI Protein Information
rho-related BTB domain-containing protein 2
UniProt Protein Name
Rho-related BTB domain-containing protein 2
UniProt Gene Name
RHOBTB2
UniProt Synonym Gene Names
DBC2; KIAA0717
UniProt Entry Name
RHBT2_HUMAN

NCBI Description

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

RHOBTB2: is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: G protein; G protein, monomeric, Rho; G protein, monomeric

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: cytosol; plasma membrane

Molecular Function: GTP binding

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction

Research Articles on RHOBTB2 / DBC2

Similar Products

Product Notes

The RHOBTB2 / DBC2 rhobtb2 (Catalog #AAA249695) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RHOBTB2 / DBC2 Antibody (aa61-110) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's RHOBTB2 / DBC2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). ELISA (1:5000) IHC-P (10 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the RHOBTB2 / DBC2 rhobtb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RHOBTB2 / DBC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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