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Western Blot (WB) (Western blot analysis of RHEB expression in Hela (A), Raji (B) whole cell lysates.)

Rabbit RHEB Polyclonal Antibody | anti-RHEB antibody

Anti-RHEB Antibody

Gene Names
RHEB; RHEB2
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
RHEB; Polyclonal Antibody; Anti-RHEB Antibody; RHEB2; GTP-binding protein Rheb; Ras homolog enriched in brain; anti-RHEB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of RHEB protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
184
Applicable Applications for anti-RHEB antibody
Western Blot (WB)
Application Notes
Western Blot: 1/500 - 1/2000
Immunogen
Recombinant full length protein of human RHEB
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of RHEB expression in Hela (A), Raji (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of RHEB expression in Hela (A), Raji (B) whole cell lysates.)
Related Product Information for anti-RHEB antibody
Rabbit polyclonal antibody to RHEB

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,497 Da
NCBI Official Full Name
GTP-binding protein Rheb
NCBI Official Synonym Full Names
Ras homolog enriched in brain
NCBI Official Symbol
RHEB
NCBI Official Synonym Symbols
RHEB2
NCBI Protein Information
GTP-binding protein Rheb
UniProt Protein Name
GTP-binding protein Rheb
Protein Family
UniProt Gene Name
RHEB
UniProt Synonym Gene Names
RHEB2
UniProt Entry Name
RHEB_HUMAN

NCBI Description

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]

Uniprot Description

Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.

Research Articles on RHEB

Similar Products

Product Notes

The RHEB rheb (Catalog #AAA8247625) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RHEB Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RHEB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1/500 - 1/2000. Researchers should empirically determine the suitability of the RHEB rheb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RHEB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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