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Western Blot (WB) (Western blot analysis of anti-C-rel (NFkB) Pab (AP6336c)in Jurkat (left) and mouse kidney (right) cell line lysate. C-rel (NFkB) (arrow) was detected using the purified Pab.)

Rabbit anti-Human, Mouse REL Polyclonal Antibody | anti-REL antibody

REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (APC)

Gene Names
REL; C-Rel
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein G Affinity Chromatography.
Synonyms
REL; Polyclonal Antibody; CT (C-Rel Proto-oncogene Protein; C-Rel protein; Proto-oncogene c-Rel) (APC); anti-REL antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human NFkB. Species Crossreactivity: mouse.
Purity/Purification
Purified by Protein G Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-REL antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the C-terminal region of human C-rel (NFkB) (KLH).
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-C-rel (NFkB) Pab (AP6336c)in Jurkat (left) and mouse kidney (right) cell line lysate. C-rel (NFkB) (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-C-rel (NFkB) Pab (AP6336c)in Jurkat (left) and mouse kidney (right) cell line lysate. C-rel (NFkB) (arrow) was detected using the purified Pab.)
Product Categories/Family for anti-REL antibody
References
1. Jain, A., et al., J. Clin. Invest. 114(11):1593-1602 (2004). 2. Xiao, Q., et al., Appl. Immunohistochem. Mol. Morphol. 12(3):211-215 (2004). 3. Houldsworth, J., et al., Blood 103(5):1862-1868 (2004). 4. Phelps, C.B., et al., Oncogene 23(6):1229-1238 (2004). 5. Bernard, D., et al., Cancer Res. 64(2):472-481 (2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,225 Da
NCBI Official Full Name
proto-oncogene c-Rel isoform 1
NCBI Official Synonym Full Names
v-rel avian reticuloendotheliosis viral oncogene homolog
NCBI Official Symbol
REL
NCBI Official Synonym Symbols
C-Rel
NCBI Protein Information
proto-oncogene c-Rel; oncogene REL, avian reticuloendotheliosis
UniProt Protein Name
Proto-oncogene c-Rel
Protein Family
UniProt Gene Name
REL
UniProt Entry Name
REL_HUMAN

Uniprot Description

REL: a proto-oncogenic transcription factor of the nuclear factor-kappaB (NFkB) group. There are five NFkB proteins in mammals (RelA/NFkB-p65, RelB, c-Rel, NF-_B1/NFkB-p105, and NF-_B2/NFkB-p100). They form a variety of homodimers and heterodimers, each of which activates its own characteristic set of genes. May play a role in differentiation and lymphopoiesis.

Protein type: Transcription factor; Oncoprotein

Chromosomal Location of Human Ortholog: 2p13-p12

Cellular Component: nucleoplasm; transcription factor complex; cytosol

Molecular Function: protein binding; chromatin binding; transcription factor activity

Biological Process: I-kappaB kinase/NF-kappaB cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-12 biosynthetic process; transcription, DNA-dependent; response to cytokine stimulus; cytokine production; innate immune response; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; inflammatory response

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Product Notes

The REL rel (Catalog #AAA6497163) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (APC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's REL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-1:500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the REL rel for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "REL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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