Rabbit anti-Human, Mouse Regulator of microtubule dynamics protein 3 Polyclonal Antibody | anti-RMDN3 antibody
Rabbit anti-human Regulator of microtubule dynamics protein 3 polyclonal Antibody(RMDN3)
IHC:1:20-1:200
Western Blot (WB)
(Western blotAll lanes: RMDN3 antibody at 4ug/mlLane 1:Hela whole cell lysateLane 2:MCF-7 whole cell lysateLane 3:mouse liver tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 53,39 kDaObserved band size: 52 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human skin using MBS1497052 at dilution 1:100)
NCBI and Uniprot Product Information
Uniprot Description
FAM82A2: a single-pass membrane protein in the mitochondrial membrane. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis. Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system. Induced by EGF, TGF-beta, retinoic acid-and 1,25-Dihydroxyvitamin D(3). Two alternatively spliced human isoforms may be produced.
Protein type: Membrane protein, integral; Mitochondrial; Apoptosis
Chromosomal Location of Human Ortholog: 15q15.1
Cellular Component: integral to membrane; microtubule; mitochondrial outer membrane; mitochondrion; nucleus; spindle pole
Molecular Function: protein binding
Biological Process: apoptosis; cell differentiation; cellular calcium ion homeostasis
Research Articles on RMDN3
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Product Notes
The RMDN3 rmdn3 (Catalog #AAA1497052) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Regulator of microtubule dynamics protein 3 polyclonal Antibody(RMDN3) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Regulator of microtubule dynamics protein 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the RMDN3 rmdn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Regulator of microtubule dynamics protein 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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