Western Blot (WB)
(Western blot analysis of RCL expression in HepG2 (A), HEK293T (B), LO2 (C), PC12 (D), AML12 (E) whole cell lysates.)
Rabbit RCL Polyclonal Antibody | anti-RCL antibody
Anti-RCL Antibody
Western Blot (WB)
(Western blot analysis of RCL expression in HepG2 (A), HEK293T (B), LO2 (C), PC12 (D), AML12 (E) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of RCL expression in HepG2 (A), HEK293T (B), LO2 (C), PC12 (D), AML12 (E) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
DNPH1: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'- monophosphates containing purine bases are preferred to those containing pyrimidine bases. Monomer and homodimer. Expression is induced by ETV1. Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers. Belongs to the deoxyribonucleoside 5'-monophosphate N- glycosidase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.2.2.-; Hydrolase
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: protein homodimerization activity; nucleoside deoxyribosyltransferase activity
Biological Process: cell proliferation; epithelial cell differentiation; nucleoside metabolic process; nucleotide metabolic process; positive regulation of cell growth; deoxyribonucleoside monophosphate catabolic process
Research Articles on RCL
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Product Notes
The RCL dnph1 (Catalog #AAA8305567) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RCL Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RCL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the RCL dnph1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RCL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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