Western Blot (WB)
(RCAN3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RCAN3 antibody detected the RCAN3 protein (arrow).)
Rabbit anti-Human RCAN3 Polyclonal Antibody | anti-RCAN3 antibody
RCAN3, CT (RCAN3, DSCR1L2, Calcipressin-3, Down syndrome candidate region 1-like protein 2, Myocyte-enriched calcineurin-interacting protein 3, Regulator of calcineurin 3) (FITC)
Gene Names
RCAN3; RCN3; MCIP3; hRCN3; DSCR1L2
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
RCAN3; Polyclonal Antibody; CT (RCAN3; DSCR1L2; Calcipressin-3; Down syndrome candidate region 1-like protein 2; Myocyte-enriched calcineurin-interacting protein 3; Regulator of calcineurin 3) (FITC); Regulator of calcineurin 3; anti-RCAN3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-RCAN3 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
RCAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from the C-terminal region of human RCAN3.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(RCAN3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RCAN3 antibody detected the RCAN3 protein (arrow).)
Western Blot (WB)
(RCAN3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RCAN3 antibody detected the RCAN3 protein (arrow).)
Immunohistochemistry (IHC)
(RCAN3 Antibody (C-term) (AP14397b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RCAN3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(RCAN3 Antibody (C-term) (AP14397b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RCAN3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-RCAN3 antibody
RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Product Categories/Family for anti-RCAN3 antibody
References
Sales, K.J., et al. Biochim. Biophys. Acta 1793(12):1917-1928(2009). Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008). Facchin, F., et al. Gene 407 (1-2), 159-168 (2008): Mulero, M.C., et al. Biochim. Biophys. Acta 1773(3):330-341(2007). Olsen, J.V., et al. Cell 127(3):635-648(2006).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,492 Da
NCBI Official Full Name
calcipressin-3
NCBI Official Synonym Full Names
RCAN family member 3
NCBI Official Symbol
RCAN3
NCBI Official Synonym Symbols
RCN3; MCIP3; hRCN3; DSCR1L2
NCBI Protein Information
calcipressin-3; OTTHUMP00000003336; Down syndrome candidate region 1-like 2; regulator of calcineurin 3 isoform 1,3,4,5; Down syndrome critical region gene 1-like 2; regulator of calcineurin 3 isoform 1a,3,4,5; regulator of calcineurin 3 isoform 1c,3,4,5;
UniProt Protein Name
Calcipressin-3
Protein Family
UniProt Gene Name
RCAN3
UniProt Synonym Gene Names
DSCR1L2; MCIP3
UniProt Entry Name
RCAN3_HUMAN
Uniprot Description
RCAN3: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Belongs to the RCAN family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 1p36.11
Molecular Function: RNA binding; troponin I binding
Biological Process: anatomical structure morphogenesis; calcium-mediated signaling
Research Articles on RCAN3
Similar Products
Product Notes
The RCAN3 rcan3 (Catalog #AAA6341018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RCAN3, CT (RCAN3, DSCR1L2, Calcipressin-3, Down syndrome candidate region 1-like protein 2, Myocyte-enriched calcineurin-interacting protein 3, Regulator of calcineurin 3) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RCAN3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RCAN3 rcan3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RCAN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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