Human transthyretin ELISA Kit | TTR elisa kit

Human transthyretin, TTR ELISA Kit

Cat. Num. AAA704931

• Gene Names: TTR; CTS; CTS1; PALB; TBPA; HEL111; HsT2651
• Reactivity: Human
• Synonyms: transthyretin; Human transthyretin; TTR ELISA Kit; Human transthyretin (TTR) ELISA kit; HsT2651; PALB; TBPA; prealbumin; amyloidosis type I; thyroxine-binding prealbumin; TTR elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of human TTR. No significant cross-reactivity or interference between human TTR and analogues was observed.
• Sequence Length: 147

• Samples: Serum, plasma, tissue homogenates
• Assay Type: Quantitative Competitive
• Detection Range: 1.56 ug/ml-25 ug/ml
• Sensitivity: < 0.78 ug/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
• Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for TTR elisa kit

Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with TTR. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for TTR. The competitive inhibition reaction is launched between with pre-coated TTR and TTR in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of TTR in the samples. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 4507725
• NCBI GeneID: 7276
• NCBI Accession #: NP_000362.1
• NCBI GenBank Nucleotide #: NM_000371.3
• UniProt Accession #: P02766; Q549C7; Q6IB96; Q9UBZ6; Q9UCM9
• Molecular Weight: 15,887 Da
• NCBI Official Full Name: transthyretin
• NCBI Official Synonym Full Names: transthyretin
• NCBI Official Symbol: TTR
• NCBI Official Synonym Symbols: CTS; CTS1; PALB; TBPA; HEL111; HsT2651
• NCBI Protein Information: transthyretin; ATTR; carpal tunnel syndrome 1; thyroxine-binding prealbumin; epididymis luminal protein 111; prealbumin, amyloidosis type I
• UniProt Protein Name: Transthyretin
• Protein Family: Transthyretin
• UniProt Gene Name: TTR
• UniProt Synonym Gene Names: PALB
• UniProt Entry Name: TTHY_HUMAN

NCBI Description

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]

Uniprot Description

Function: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.1 PublicationManual assertion based on experiment in:Ref.29