Western Blot (WB)
(Western Blot analysis of RBPJK on human colon tissue lysates using anti-RBPJK antibody at 1/500 dilution.)
Rabbit anti-Human RBPJK Polyclonal Antibody | anti-RBPJK antibody
RBPJK Polyclonal Antibody
Gene Names
RBPJ; SUH; csl; AOS3; CBF1; KBF2; CBF-1; RBP-J; RBPJK; IGKJRB; RBP-JK; RBPSUH; IGKJRB1; RBP-J kappa
Reactivity
Human
Applications
Western Blot
Purity
ProA affinity purified
Synonyms
RBPJK; Polyclonal Antibody; RBPJK Polyclonal Antibody; RBP-J; RBP-JK; RBPJ; IGKJRB; IGKJRB1; RBPSUH; AI843960; AOS3; CBF 1; CBF-1; CBF1; csl; J kappa recombination signal binding protein; J kappa-recombination signal-binding protein; KBF2; NY REN 30 antigen; RBP J; RBP J kappa; RBP JK; RBP-J kappa; Rbpj; recombination signal binding protein for immunoglobulin kappa J region; Recombining binding protein suppressor of hairless; Renal carcinoma antigen NY-REN-30; SUH; anti-RBPJK antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
RBPJK polyclonal antibody detects endogenous levels of RBPJK protein.
Purity/Purification
ProA affinity purified
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
500
Applicable Applications for anti-RBPJK antibody
Western Blot (WB)
Application Notes
WB: 1:1,000-1:5,000
Immunogen
Recombinant protein
Preparation and Storage
Store at 4 degree C after thawing.
Aliquot store at -20 degree C or -80 degree C.
Avoid repeated freeze/thaw cycles.
Aliquot store at -20 degree C or -80 degree C.
Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of RBPJK on human colon tissue lysates using anti-RBPJK antibody at 1/500 dilution.)
Western Blot (WB)
(Western Blot analysis of RBPJK on human colon tissue lysates using anti-RBPJK antibody at 1/500 dilution.)
Related Product Information for anti-RBPJK antibody
Recombination signal binding protein Jkappa (RBP-Jkappa), also designated KBF2 or CBF1, is the mammalian homolog of the Drosophila suppressor of hairless (Su(H)), a protein involved in the development of the peripheral nervous system. RBP-Jkappa is ubiquitously expressed in mammalian tissues and is involved in the regulation of gene expression. RBP-Jkappa has been shown to directly interact with the intercellular domain of the cell surface receptor Notch 1. Proteolytically cleaved Notch 1 translocates to the nucleus, where it binds DNA-bound RBP-Jkappa and activates transcription of target genes. These genes include NFkappaB p52 and the Epstein-Barr virus (EBV) protein EBNA-2, both of which contain RBP-Jkappa-binding sequences within their promoter regions.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55kDa
NCBI Official Full Name
recombining binding protein suppressor of hairless isoform 1
NCBI Official Synonym Full Names
recombination signal binding protein for immunoglobulin kappa J region
NCBI Official Symbol
RBPJ
NCBI Official Synonym Symbols
SUH; csl; AOS3; CBF1; KBF2; CBF-1; RBP-J; RBPJK; IGKJRB; RBP-JK; RBPSUH; IGKJRB1; RBP-J kappa
NCBI Protein Information
recombining binding protein suppressor of hairless
UniProt Protein Name
Recombining binding protein suppressor of hairless
UniProt Gene Name
RBPJ
UniProt Synonym Gene Names
IGKJRB; IGKJRB1; RBPJK; RBPSUH; RBP-J; RBP-JK
UniProt Entry Name
SUH_HUMAN
NCBI Description
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
Research Articles on RBPJK
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Product Notes
The RBPJK rbpj (Catalog #AAA3013354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RBPJK Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RBPJK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1,000-1:5,000. Researchers should empirically determine the suitability of the RBPJK rbpj for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBPJK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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