Rabbit anti-Human, Mouse RBMS3 Polyclonal Antibody | anti-RBMS3 antibody

RBMS3 Antibody

Cat. Num. AAA7127664

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purification
• Synonyms: RBMS3; Polyclonal Antibody; RBMS3 Antibody; RNA binding motif; single stranded interacting protein 3; anti-RBMS3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol

• Applicable Applications for anti-RBMS3 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: ELISA: 1:1000-1:5000; WB: 1:500-1:2000; IHC: 1:25-1:100
• Immunogen: Synthetic peptide of human RBMS3
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7127664(RBMS3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7127664(RBMS3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Human liver cancer tissue, Primary antibody: MBS7127664(RBMS3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

NCBI and Uniprot Product Information

• NCBI GI #: 74762382
• NCBI GeneID: 27303
• UniProt Accession #: Q6XE24; O75876; Q17RI0; Q6XE23; A8K9S4; B7ZL17; G5E9J9
• Molecular Weight: 437
• NCBI Official Full Name: RNA-binding motif, single-stranded-interacting protein 3
• NCBI Official Synonym Full Names: RNA binding motif, single stranded interacting protein 3
• NCBI Official Symbol: RBMS3
• NCBI Protein Information: RNA-binding motif, single-stranded-interacting protein 3; RNA-binding protein
• UniProt Protein Name: RNA-binding motif, single-stranded-interacting protein 3
• Protein Family: RNA-binding motif, single-stranded-interacting protein
• UniProt Gene Name: RBMS3
• UniProt Entry Name: RBMS3_HUMAN

NCBI Description

This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Uniprot Description

RBMS3: Binds poly(A) and poly(U) oligoribonucleotides. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 3p24-p23

Cellular Component: cytoplasm

Molecular Function: mRNA 3'-UTR binding; nucleotide binding

Biological Process: positive regulation of translation