Rabbit anti-Human RBBP7 Polyclonal Antibody | anti-RBBP7 antibody

RBBP7, ID (RBBP7, RBAP46, Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, Retinoblastoma-binding protein p46) (PE)

Cat. Num. AAA6340618

• Gene Names: RBBP7; RbAp46
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RBBP7; Polyclonal Antibody; ID (RBBP7; RBAP46; Histone-binding protein RBBP7; Histone acetyltransferase type B subunit 2; Nucleosome-remodeling factor subunit RBAP46; Retinoblastoma-binding protein 7; Retinoblastoma-binding protein p46) (PE); Retinoblastoma-binding protein p46; anti-RBBP7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-RBBP7 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: RBBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human RBBP7.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(RBBP7 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RBBP7 antibody detected the RBBP7 protein (arrow).)

Western Blot (WB)

(Western blot analysis of RBBP7 (arrow) using rabbit polyclonal RBBP7 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene.)

Related Product Information for anti-RBBP7 antibody

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Product Categories/Family for anti-RBBP7 antibody

Antibodies; Retinoblastoma Proteins

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Saade, E., et al. Proteomics 9(21):4934-4943(2009). Wang, C.L., et al. J. Proteome Res. 8(10):4428-4440(2009). Li, R., et al. EMBO J. 28(18):2763-2776(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 4506439
• NCBI GeneID: 5931
• NCBI Accession #: NP_002884.1
• NCBI GenBank Nucleotide #: NM_002893.3
• UniProt Accession #: Q16576
• Molecular Weight: 47,820 Da
• NCBI Official Full Name: histone-binding protein RBBP7 isoform 2
• NCBI Official Synonym Full Names: retinoblastoma binding protein 7
• NCBI Official Symbol: RBBP7
• NCBI Official Synonym Symbols: RbAp46
• NCBI Protein Information: histone-binding protein RBBP7
• UniProt Protein Name: Histone-binding protein RBBP7
• Protein Family: Histone-binding protein
• UniProt Gene Name: RBBP7
• UniProt Synonym Gene Names: RBAP46; RBBP-7
• UniProt Entry Name: RBBP7_HUMAN

NCBI Description

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]