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Western Blot (WB) (Western blot analysis RASIP1 using HeLa whole cell lysates)

Rabbit anti-Human RASIP1 Polyclonal Antibody | anti-RASIP1 antibody

RASIP1 Antibody

Gene Names
RASIP1; RAIN
Reactivity
Human
Applications
Western Blot
Synonyms
RASIP1; Polyclonal Antibody; RASIP1 Antibody; Ras-interacting protein 1; Ras interacting protein 1; RAIN; anti-RASIP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
RASIP1 Antibody detects endogenous levels of total RASIP1
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
963
Applicable Applications for anti-RASIP1 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human RASIP1
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis RASIP1 using HeLa whole cell lysates)

Western Blot (WB) (Western blot analysis RASIP1 using HeLa whole cell lysates)
Product Categories/Family for anti-RASIP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
103,457 Da
NCBI Official Full Name
ras-interacting protein 1
NCBI Official Synonym Full Names
Ras interacting protein 1
NCBI Official Symbol
RASIP1
NCBI Official Synonym Symbols
RAIN
NCBI Protein Information
ras-interacting protein 1
UniProt Protein Name
Ras-interacting protein 1
Protein Family
UniProt Gene Name
RASIP1
UniProt Synonym Gene Names
Rain
UniProt Entry Name
RAIN_HUMAN

Uniprot Description

RASIP1: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS- mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Protein type: Cell cycle regulation; GAPs; GAPs, Ras

Chromosomal Location of Human Ortholog: 19q13.33

Biological Process: angiogenesis; branching morphogenesis of a tube; negative regulation of autophagy; regulation of GTPase activity; vasculogenesis

Research Articles on RASIP1

Similar Products

Product Notes

The RASIP1 rasip1 (Catalog #AAA9419568) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RASIP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RASIP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the RASIP1 rasip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RASIP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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