Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blot analysis of Ras-GRF1 in lysates of Human hippocampus, using Ras-GRF1 Antibody(AF4714).)

Rabbit anti-Human Ras-GRF1 Polyclonal Antibody | anti-Ras-GRF1 antibody

Ras-GRF1 Antibody

Gene Names
Rasgrf1; Gnrp; Grf1; p190; CDC25; P190-A; CDC25Mm; Grfbeta; AI844718; Ras-GRF1; p190RhoGEF
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Synonyms
Ras-GRF1; Polyclonal Antibody; Ras-GRF1 Antibody; CDC25; CDC25L; GNRP; GRF1; GRF55; Guanine nucleotide exchange factor; Guanine nucleotide releasing factor 55KD; Guanine nucleotide releasing protein; guanine nucleotide-releasing factor 1; Guanine nucleotide-releasing protein; H GRF55; HGRF55; PP13187; Ras protein specific guanine nucleotide releasing factor 1; Ras specific guanine nucleotide releasing factor; Ras specific guanine nucleotide releasing factor CDC25 homolog; Ras specific nucleotide exchange factor CDC25; Ras-specific guanine nucleotide-releasing factor 1; Ras-specific nucleotide exchange factor CDC25; RASGRF1; RGRF1_HUMAN; anti-Ras-GRF1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Ras-GRF1 Antibody detects endogenous levels of total Ras-GRF1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-Ras-GRF1 antibody
Western Blot (WB), Peptide ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Peptide ELISA: 1:20,000-1:40,000
Immunogen
A synthesized peptide derived from human Ras-GRF1, corresponding to a region within the internal amino acids.
Conjugation
Unconjugated
Fragment
Fab fragment
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of Ras-GRF1 in lysates of Human hippocampus, using Ras-GRF1 Antibody(AF4714).)

Western Blot (WB) (Western blot analysis of Ras-GRF1 in lysates of Human hippocampus, using Ras-GRF1 Antibody(AF4714).)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
144,102 Da
NCBI Official Full Name
ras-specific guanine nucleotide-releasing factor 1 isoform 1
NCBI Official Synonym Full Names
RAS protein-specific guanine nucleotide-releasing factor 1
NCBI Official Symbol
Rasgrf1
NCBI Official Synonym Symbols
Gnrp; Grf1; p190; CDC25; P190-A; CDC25Mm; Grfbeta; AI844718; Ras-GRF1; p190RhoGEF
NCBI Protein Information
ras-specific guanine nucleotide-releasing factor 1
UniProt Protein Name
Ras-specific guanine nucleotide-releasing factor 1
UniProt Gene Name
Rasgrf1
UniProt Synonym Gene Names
Cdc25; Grf1; Ras-GRF1; GNRP
UniProt Entry Name
RGRF1_MOUSE

Uniprot Description

RASGRF1: a guanine nucleotide exchange factor (GEF). Stimulates the dissociation of GDP from RAS protein. Activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit in the mouse brain,. The signaling pathway mediated by this protein may be important for long-term memory. Two alternatively spliced variants have been reported.

Protein type: GEFs; GEFs, Ras

Cellular Component: growth cone; intracellular; cytosol

Molecular Function: protein C-terminus binding; protein binding; Rho guanyl-nucleotide exchange factor activity; glutamate receptor binding; guanyl-nucleotide exchange factor activity; protein kinase binding

Biological Process: regulation of Ras protein signal transduction; cell proliferation; regulation of Rac protein signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; regulation of Rho protein signal transduction; regulation of synaptic plasticity; positive regulation of Ras protein signal transduction; neurite development; positive regulation of GTPase activity; regulation of neuronal synaptic plasticity

Research Articles on Ras-GRF1

Similar Products

Product Notes

The Ras-GRF1 rasgrf1 (Catalog #AAA9613422) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Ras-GRF1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ras-GRF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Peptide ELISA (EIA). WB: 1:500-1:2000 Peptide ELISA: 1:20,000-1:40,000. Researchers should empirically determine the suitability of the Ras-GRF1 rasgrf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ras-GRF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.