Rabbit anti-Human RAP1GDS1 Polyclonal Antibody | anti-RAP1GDS1 antibody

RAP1GDS1, ID (RAP1GDS1, Rap1 GTPase-GDP dissociation stimulator 1, Exchange factor smgGDS, SMG GDS protein, SMG P21 stimulatory GDP/GTP exchange protein)

Cat. Num. AAA645681

• Gene Names: RAP1GDS1; GDS1; SmgGDS
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: RAP1GDS1; Polyclonal Antibody; ID (RAP1GDS1; Rap1 GTPase-GDP dissociation stimulator 1; Exchange factor smgGDS; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein); Anti -RAP1GDS1; anti-RAP1GDS1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-RAP1GDS1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:10-50
• Immunogen: RAP1GDS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-252 amino acids from the Central region of human RAP1GDS1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(RAP1GDS1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAP1GDS1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(RAP1GDS1 Antibody (Center) western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAP1GDS1 antibody detected the RAP1GDS1 protein (arrow).)

Related Product Information for anti-RAP1GDS1 antibody

The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).

Product Categories/Family for anti-RAP1GDS1 antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 71121148
• NCBI GeneID: 5910
• UniProt Accession #: P52306; Q499L7; Q4KMV2; Q4QQI8; Q9BUW9; Q9BUX6; Q9NYM2; Q9NZA8; E9PH06; G5E9P9
• Molecular Weight: 66,317 Da
• NCBI Official Full Name: RAP1GDS1 protein
• NCBI Official Synonym Full Names: RAP1, GTP-GDP dissociation stimulator 1
• NCBI Official Symbol: RAP1GDS1
• NCBI Official Synonym Symbols: GDS1; SmgGDS
• NCBI Protein Information: rap1 GTPase-GDP dissociation stimulator 1; SMG GDS protein; exchange factor smgGDS; SMG P21 stimulatory GDP/GTP exchange protein
• UniProt Protein Name: Rap1 GTPase-GDP dissociation stimulator 1
• Protein Family: Rap1 GTPase-GDP dissociation stimulator
• UniProt Gene Name: RAP1GDS1
• UniProt Entry Name: GDS1_HUMAN

NCBI Description

The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010]

Uniprot Description

Function: Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.

Sequence similarities: Contains 5 ARM repeats.