Immunohistochemistry (IHC)
(RAP1GDS1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAP1GDS1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human RAP1GDS1 Polyclonal Antibody | anti-RAP1GDS1 antibody
RAP1GDS1, ID (RAP1GDS1, Rap1 GTPase-GDP dissociation stimulator 1, Exchange factor smgGDS, SMG GDS protein, SMG P21 stimulatory GDP/GTP exchange protein) (PE)
Gene Names
RAP1GDS1; GDS1; SmgGDS
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
RAP1GDS1; Polyclonal Antibody; ID (RAP1GDS1; Rap1 GTPase-GDP dissociation stimulator 1; Exchange factor smgGDS; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein) (PE); SMG P21 stimulatory GDP/GTP exchange protein; anti-RAP1GDS1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-RAP1GDS1 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
RAP1GDS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-252 amino acids from the Central region of human RAP1GDS1.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Immunohistochemistry (IHC)
(RAP1GDS1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAP1GDS1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(RAP1GDS1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAP1GDS1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB)
(RAP1GDS1 Antibody (Center) western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAP1GDS1 antibody detected the RAP1GDS1 protein (arrow).)
Western Blot (WB)
(RAP1GDS1 Antibody (Center) western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAP1GDS1 antibody detected the RAP1GDS1 protein (arrow).)
Related Product Information for anti-RAP1GDS1 antibody
The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).
Product Categories/Family for anti-RAP1GDS1 antibody
References
Schonherr, C., et al. Oncogene 29(19):2817-2830(2010). Branham, M.T., et al. J. Biol. Chem. 284(37):24825-24839(2009). Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009). Tew, G.W., et al. J. Biol. Chem. 283(2):963-976(2008). Tiwari, S., et al. Blood 103(7):2661-2667(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
rap1 GTPase-GDP dissociation stimulator 1 isoform 6
NCBI Official Synonym Full Names
Rap1 GTPase-GDP dissociation stimulator 1
NCBI Official Symbol
RAP1GDS1
NCBI Official Synonym Symbols
GDS1; SmgGDS
NCBI Protein Information
rap1 GTPase-GDP dissociation stimulator 1
UniProt Protein Name
Rap1 GTPase-GDP dissociation stimulator 1
Protein Family
UniProt Gene Name
RAP1GDS1
UniProt Entry Name
GDS1_HUMAN
NCBI Description
The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010]
Uniprot Description
Function: Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.
Sequence similarities: Contains 5 ARM repeats.
Research Articles on RAP1GDS1
Similar Products
Product Notes
The RAP1GDS1 rap1gds1 (Catalog #AAA6340272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAP1GDS1, ID (RAP1GDS1, Rap1 GTPase-GDP dissociation stimulator 1, Exchange factor smgGDS, SMG GDS protein, SMG P21 stimulatory GDP/GTP exchange protein) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAP1GDS1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RAP1GDS1 rap1gds1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAP1GDS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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