NCBI and Uniprot Product Information
Uniprot Description
RANBP10: Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function. May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway. Belongs to the RANBP9/10 family.
Protein type: GEFs; GEFs, Ras; GAPs; GAPs, Ras
Chromosomal Location of Human Ortholog: 16q22.1
Cellular Component: cytoplasmic microtubule; cytosol; nucleus
Molecular Function: Ran guanyl-nucleotide exchange factor activity; beta-tubulin binding; Ran GTPase binding
Biological Process: microtubule cytoskeleton organization and biogenesis
Research Articles on RANBP10
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Product Notes
The RANBP10 ranbp10 (Catalog #AAA9433287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RANBP10 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RANBP10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the RANBP10 ranbp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RANBP10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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