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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using RANBP10 antibody.)

Rabbit anti-Human, Mouse RANBP10 Polyclonal Antibody | anti-RANBP10 antibody

RANBP10 Polyclonal Antibody

Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity purification
Synonyms
RANBP10; Polyclonal Antibody; RANBP10 Polyclonal Antibody; anti-RANBP10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 50% glycerol, pH7.4
Applicable Applications for anti-RANBP10 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human RANBP10 (NP_065901.1).
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using RANBP10 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using RANBP10 antibody.)
Related Product Information for anti-RANBP10 antibody
RAN is a small GTPase involved in the assembly of microtubules to form mitotic spindles. The protein encoded by this gene is a cytoplasmic guanine nucleotide exchange factor (GEF) that binds beta-tubulin and has GEF activity toward RAN. The encoded protein plays a role in the formation of noncentrosomal microtubules. In addition, this protein may be involved in the regulation of D (1) receptor signaling by protein kinase C delta and protein kinase C gamma. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Product Categories/Family for anti-RANBP10 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
64,542 Da
NCBI Official Full Name
ran-binding protein 10
NCBI Official Synonym Full Names
RAN binding protein 10
NCBI Official Symbol
RANBP10
NCBI Protein Information
ran-binding protein 10
UniProt Protein Name
Ran-binding protein 10
Protein Family
UniProt Gene Name
RANBP10
UniProt Synonym Gene Names
KIAA1464; RanBP10
UniProt Entry Name
RBP10_HUMAN

Uniprot Description

RANBP10: Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function. May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway. Belongs to the RANBP9/10 family.

Protein type: GEFs; GEFs, Ras; GAPs; GAPs, Ras

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasmic microtubule; cytosol; nucleus

Molecular Function: Ran guanyl-nucleotide exchange factor activity; beta-tubulin binding; Ran GTPase binding

Biological Process: microtubule cytoskeleton organization and biogenesis

Research Articles on RANBP10

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Product Notes

The RANBP10 ranbp10 (Catalog #AAA9433287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RANBP10 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RANBP10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the RANBP10 ranbp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RANBP10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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