Western Blot (WB)
(Western BlotPositive WB detected in: HepG2 whole cell lysateAll lanes: RAI1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 204,199,176,105 KDaObserved band size: 204 KDa)
Rabbit anti-Human RAI1 Polyclonal Antibody | anti-RAI1 antibody
RAI1 Antibody
IHC: 1:20-1:200
IF: 1:50-1:200
Western Blot (WB)
(Western BlotPositive WB detected in: HepG2 whole cell lysateAll lanes: RAI1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 204,199,176,105 KDaObserved band size: 204 KDa)
Western Blot (WB)
(Western BlotPositive WB detected in: HepG2 whole cell lysateAll lanes: RAI1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 204,199,176,105 KDaObserved band size: 204 KDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human heart tissue using MBS7052953 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human heart tissue using MBS7052953 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7052953 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7052953 at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7052953 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7052953 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It is highly similar to its mouse counterpart and is expressed at high levels mainly in neuronal tissues. The protein encoded by this gene includes a polymorphic polyglutamine tract in the N-terminal domain. Expression of the mouse counterpart in neurons is induced by retinoic acid. This gene is associated with both the severity of the phenotype and the response to medication in schizophrenic patients. [provided by RefSeq, Jul 2008]
Uniprot Description
RAI1: May function as a transcriptional regulator. Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. May be important for embryonic and postnatal development. May be involved in neuronal differentiation. Defects in RAI1 are a cause of Smith-Magenis syndrome (SMS). SMS is characterized by congenital mental retardation associated with development and growth delays. Affected persons have characteristic behavioral abnormalities, including self-injurious behaviors and sleep disturbance, and distinct craniofacial and skeletal anomalies. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: mitochondrion; nucleoplasm; nucleus
Molecular Function: protein binding; transcription factor activity
Biological Process: circadian regulation of gene expression; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent
Disease: Smith-magenis Syndrome
Research Articles on RAI1
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Product Notes
The RAI1 rai1 (Catalog #AAA7052953) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAI1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAI1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:5000 IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the RAI1 rai1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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