Rabbit RAD51AP1 Polyclonal Antibody | anti-RAD51AP1 antibody
RAD51AP1 Antibody
Gene Names
RAD51AP1; PIR51
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
RAD51AP1; Polyclonal Antibody; RAD51AP1 Antibody; 2510006L10Rik; MGC156698; OTTMUSP00000028651; PIR51; R51A1_HUMAN; RAB22; RAD51 associated protein 1; RAD51 interacting protein; RAD51-associated protein 1; RAD51-interacting protein; Rad51ap1; anti-RAD51AP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
RAD51AP1 Antibody detects endogenous levels of total RAD51AP1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RAD51AP1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Subunit Structure
Isoform 2 interacts with RAD51. Interacts with PALB2. Interacts (via C-terminal region) with RAD51; the interaction is direct.
Tissue Specificity
Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.
Function
May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.
Note
Colocalizes with RAD51 to multiple nuclear foci.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,142 Da
NCBI Official Full Name
RAD51-associated protein 1 isoform b
NCBI Official Synonym Full Names
RAD51 associated protein 1
NCBI Official Symbol
RAD51AP1
NCBI Official Synonym Symbols
PIR51
NCBI Protein Information
RAD51-associated protein 1; RAD51AP1; RAD51-interacting protein
UniProt Protein Name
RAD51-associated protein 1
Protein Family
UniProt Gene Name
RAD51AP1
UniProt Entry Name
R51A1_HUMAN
Uniprot Description
RAD51AP1: May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 12p13.2-p13.1
Cellular Component: nucleus
Molecular Function: protein binding; RNA binding; double-stranded DNA binding; single-stranded DNA binding
Biological Process: DNA repair; double-strand break repair via homologous recombination
Research Articles on RAD51AP1
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Product Notes
The RAD51AP1 rad51ap1 (Catalog #AAA9629464) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAD51AP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAD51AP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the RAD51AP1 rad51ap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAD51AP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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