Rabbit RABAC1 Polyclonal Antibody | anti-RABAC1 antibody
RABAC1 Antibody
Gene Names
RABAC1; PRA1; YIP3; PRAF1
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
RABAC1; Polyclonal Antibody; RABAC1 Antibody; PRA1 domain family 1; PRA1 family protein 1; PRAF1; PRAF1_HUMAN; prenylated Rab acceptor 1; Prenylated Rab acceptor protein 1; Rab acceptor 1 (prenylated); YIP3; anti-RABAC1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
RABAC1 Antibody detects endogenous levels of RABAC1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RABAC1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human RABAC1.
Conjugation
Unconjugated
Similarity
Belongs to the PRA1 family.
Subunit Structure
Homodimer. Interacts with VAMP2 (synaptobrevin-2), GDI1, and PCLO (By similarity). Interacts specifically with prenylated Rab proteins; strongly with RAB4B, RAB5A and RAB5C, and weakly with RAB4A, RAB6, RAB7A, RAB17 and RAB22. Interacts with NDRG1.
Tissue Specificity
Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach.
Function
General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI.
Note
According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-RABAC1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
185
NCBI Official Full Name
Prenylated Rab acceptor protein 1
NCBI Official Synonym Full Names
Rab acceptor 1 (prenylated)
NCBI Official Symbol
RABAC1
NCBI Official Synonym Symbols
PRA1; YIP3; PRAF1
NCBI Protein Information
prenylated Rab acceptor protein 1; PRA1 domain family 1; PRA1 family protein 1; prenylated Rab acceptor 1
UniProt Protein Name
Prenylated Rab acceptor protein 1
Protein Family
UniProt Gene Name
RABAC1
UniProt Synonym Gene Names
PRA1; PRAF1
UniProt Entry Name
PRAF1_HUMAN
Uniprot Description
RABAC1: General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. Belongs to the PRA1 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: Golgi apparatus; synaptic vesicle; membrane; integral to membrane; plasma membrane; cell junction
Molecular Function: protein C-terminus binding; identical protein binding; protein binding
Research Articles on RABAC1
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Product Notes
The RABAC1 rabac1 (Catalog #AAA9630762) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABAC1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RABAC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the RABAC1 rabac1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RABAC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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