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Western Blot (WB) (RAB5C Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RAB5C antibody detected the RAB5C protein (arrow).)

Rabbit anti-Human RAB5C Polyclonal Antibody | anti-RAB5C antibody

RAB5C, CT (RAB5C, RABL, Ras-related protein Rab-5C, L1880, RAB5L) (APC)

Gene Names
RAB5C; RABL; L1880; RAB5L; RAB5CL
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
RAB5C; Polyclonal Antibody; CT (RAB5C; RABL; Ras-related protein Rab-5C; L1880; RAB5L) (APC); RAB5L; anti-RAB5C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-RAB5C antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
RAB5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-207 amino acids from the C-terminal region of human RAB5C.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(RAB5C Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RAB5C antibody detected the RAB5C protein (arrow).)

Western Blot (WB) (RAB5C Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RAB5C antibody detected the RAB5C protein (arrow).)

Immunohistochemistry (IHC)

(RAB5C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAB5C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (RAB5C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RAB5C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-RAB5C antibody
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).
Product Categories/Family for anti-RAB5C antibody
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006). Merithew, E., et al. J. Biol. Chem. 278(10):8494-8500(2003). Clemens, D.L., et al. Infect. Immun. 68(5):2671-2684(2000). Bucci, C., et al. Biochem. Biophys. Res. Commun. 258(3):657-662(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
ras-related protein Rab-5C isoform a
NCBI Official Synonym Full Names
RAB5C, member RAS oncogene family
NCBI Official Symbol
RAB5C
NCBI Official Synonym Symbols
RABL; L1880; RAB5L; RAB5CL
NCBI Protein Information
ras-related protein Rab-5C
UniProt Protein Name
Ras-related protein Rab-5C
Protein Family
UniProt Gene Name
RAB5C
UniProt Synonym Gene Names
RABL
UniProt Entry Name
RAB5C_HUMAN

NCBI Description

Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010]

Uniprot Description

RAB5C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric, Rab; Motility/polarity/chemotaxis; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; endocytic vesicle; early endosome membrane; early endosome; plasma membrane; melanosome; lipid particle

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: intracellular protein transport; metabolic process; regulation of endocytosis; plasma membrane to endosome transport; Rab protein signal transduction

Research Articles on RAB5C

Similar Products

Product Notes

The RAB5C rab5c (Catalog #AAA6339867) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAB5C, CT (RAB5C, RABL, Ras-related protein Rab-5C, L1880, RAB5L) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAB5C can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RAB5C rab5c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB5C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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