Rabbit RAB3B Polyclonal Antibody | anti-RAB3B antibody
RAB3B Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
RAB3B; Polyclonal Antibody; RAB3B Antibody; Brain antigen RAB3B; RAB3B member RAS oncogene family; RAB3B_HUMAN; ras related protein Rab 3B; Ras-related protein Rab-3B; anti-RAB3B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
RAB3B Antibody detects endogenous levels of total RAB3B.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RAB3B antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the small GTPase superfamily. Rab family.
Post Translational Modifications
Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitor GDI2.
Subunit Structure
Interacts with RIMS1, RIMS2, RPH3A and RPH3AL. The GTP-bound form interacts with GAS8/DRC4 (via coiled-coil domains) (By similarity). Interacts with GDI2, CHM and CHML; phosphorylation at Thr-86 disrupts these interactions.
Function
Protein transport. Probably involved in vesicular traffic (By similarity).
Note
Colocalizes with GAS8/DRC4 in the Golgi apparatus.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-RAB3B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24,758 Da
NCBI Official Full Name
ras-related protein Rab-3B
NCBI Official Synonym Full Names
RAB3B, member RAS oncogene family
NCBI Official Symbol
RAB3B
NCBI Protein Information
ras-related protein Rab-3B; brain antigen RAB3B
UniProt Protein Name
Ras-related protein Rab-3B
Protein Family
UniProt Gene Name
RAB3B
UniProt Entry Name
RAB3B_HUMAN
Uniprot Description
RAB3B: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein, monomeric, Rab; G protein, monomeric; G protein
Chromosomal Location of Human Ortholog: 1p32-p31
Cellular Component: synaptic vesicle; secretory granule membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; cytosol; endosome; vesicle
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding
Biological Process: regulation of exocytosis; antigen processing and presentation; intracellular protein transport; synaptic vesicle exocytosis; positive regulation of dopamine uptake; protein secretion; peptidyl-cysteine methylation; Rab protein signal transduction; vesicle docking during exocytosis
Research Articles on RAB3B
Similar Products
Product Notes
The RAB3B rab3b (Catalog #AAA9629734) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAB3B Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAB3B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the RAB3B rab3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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