Rabbit anti-Human RAB2B Polyclonal Antibody | anti-RAB2B antibody

RAB2B, ID (RAB2B, Ras-related protein Rab-2B) (Biotin)

Cat. Num. AAA6339703

• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RAB2B; Polyclonal Antibody; ID (RAB2B; Ras-related protein Rab-2B) (Biotin); Ras-related protein Rab-2B; anti-RAB2B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-RAB2B antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: RAB2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-131 amino acids from the Central region of human RAB2B.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(RAB2B Antibody (Center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the RAB2B antibody detected the RAB2B protein (arrow).)

Related Product Information for anti-RAB2B antibody

Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM].

Product Categories/Family for anti-RAB2B antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins

References

Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005). Fu, G.K., et al. Genomics 84(1):205-210(2004). Ni, X., et al. J. Hum. Genet. 47(10):548-551(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 21361884
• NCBI GeneID: 84932
• NCBI Accession #: NP_116235.2
• NCBI GenBank Nucleotide #: NM_032846.3
• UniProt Accession #: Q8WUD1; B2RD03; D3DS24
• Molecular Weight: 24,214 Da
• NCBI Official Full Name: ras-related protein Rab-2B isoform 1
• NCBI Official Synonym Full Names: RAB2B, member RAS oncogene family
• NCBI Official Symbol: RAB2B
• NCBI Protein Information: ras-related protein Rab-2B; RAS family, member RAB2B; GTP-binding protein RAB2B
• UniProt Protein Name: Ras-related protein Rab-2B
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB2B
• UniProt Entry Name: RAB2B_HUMAN

NCBI Description

Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]

Uniprot Description

RAB2B: Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential). Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric; G protein, monomeric, Rab; G protein

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; plasma membrane

Molecular Function: GTPase activity; GDP binding; GTP binding

Biological Process: vesicle-mediated transport; intracellular protein transport; metabolic process; Rab protein signal transduction; positive regulation of exocytosis