Western Blot (WB)
(WB Suggested Anti-RAB11FIP2 Antibody Titration: 0.2-1 ug/mlPositive Control: COLO205 cell lysate)
Rabbit RAB11FIP2 Polyclonal Antibody | anti-RAB11FIP2 antibody
RAB11FIP2 antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-RAB11FIP2 Antibody Titration: 0.2-1 ug/mlPositive Control: COLO205 cell lysate)
Western Blot (WB)
(WB Suggested Anti-RAB11FIP2 Antibody Titration: 0.2-1 ug/mlPositive Control: COLO205 cell lysate)
Target Description: RAB11FIP2 is a Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane.RAB11FIP2 is also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).
NCBI and Uniprot Product Information
Uniprot Description
RAB11FIP2: a Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA). Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Phosphorylation by MARK2 may affect the establishment of epithelial polarity.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 10q26.11
Cellular Component: nucleoplasm; cytoplasmic vesicle membrane; intracellular membrane-bound organelle; recycling endosome membrane; plasma membrane; endosome
Molecular Function: protein binding; protein homodimerization activity; protein kinase binding; Rab GTPase binding
Biological Process: regulated secretory pathway; establishment of cell polarity; water transport; renal water homeostasis; transmembrane transport
Research Articles on RAB11FIP2
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Product Notes
The RAB11FIP2 rab11fip2 (Catalog #AAA3212053) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAB11FIP2 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAB11FIP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the RAB11FIP2 rab11fip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LLIQGSPEKY ILFLIVMHRS LVGLDKFLGQ VAINLNDIFE DKQRRKTEWF. It is sometimes possible for the material contained within the vial of "RAB11FIP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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