Rabbit PYCR2 Polyclonal Antibody | anti-PYCR2 antibody
PYCR2 Antibody
Gene Names
PYCR2; P5CR2
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PYCR2; Polyclonal Antibody; PYCR2 Antibody; 1810018M05Rik; FLJ54750; Leftb; OTTHUMP00000035614; P5C reductase 2; P5CR 2; P5CR2; P5CR2_HUMAN; PYCR 2; Pyrroline 5 carboxylate reductase 2; Pyrroline 5 carboxylate reductase family member 2; Pyrroline 5 carboxylate reductase isoform; Pyrroline-5-carboxylate reductase 2; RP4-559A3.4; anti-PYCR2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PYCR2 Antibody detects endogenous levels of PYCR2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PYCR2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human PYCR2.
Conjugation
Unconjugated
Similarity
Belongs to the pyrroline-5-carboxylate reductase family.
Subunit Structure
Homodecamer; composed of 5 homodimers (Probable). Interacts with LTO1.
Tissue Specificity
Detected in erythrocytes (at protein level). Expressed in fetal brain.
Function
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Involved in cellular response to oxidative stress.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-PYCR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
320
NCBI Official Full Name
Pyrroline-5-carboxylate reductase 2
NCBI Official Synonym Full Names
pyrroline-5-carboxylate reductase family, member 2
NCBI Official Symbol
PYCR2
NCBI Official Synonym Symbols
P5CR2
NCBI Protein Information
pyrroline-5-carboxylate reductase 2; P5C reductase 2; pyrroline 5-carboxylate reductase isoform
UniProt Protein Name
Pyrroline-5-carboxylate reductase 2
Protein Family
UniProt Gene Name
PYCR2
UniProt Synonym Gene Names
P5C reductase 2; P5CR 2
UniProt Entry Name
P5CR2_HUMAN
NCBI Description
This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
Uniprot Description
PYCR2: Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Belongs to the pyrroline-5-carboxylate reductase family.
Protein type: Amino Acid Metabolism - arginine and proline; Oxidoreductase; EC 1.5.1.2
Chromosomal Location of Human Ortholog: 1q42.12
Cellular Component: cytoplasm
Molecular Function: pyrroline-5-carboxylate reductase activity
Disease: Leukodystrophy, Hypomyelinating, 10
Similar Products
Product Notes
The PYCR2 pycr2 (Catalog #AAA9630702) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PYCR2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PYCR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the PYCR2 pycr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PYCR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
