Rabbit PTPN20B Polyclonal Antibody | anti-PTPN20B antibody

PTPN20B Polyclonal Antibody

Cat. Num. AAA2526372

• Gene Names: PTPN20B; CT126; PTPN20A; hPTPN20; bA42B19.1; bA142I17.1
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: PTPN20B; Polyclonal Antibody; PTPN20B Polyclonal Antibody; CT126; PTPN20A; hPTPN20; bA42B19.1; bA142I17.1; anti-PTPN20B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 2mg/mL (varies by lot)
• Sequence Length: 145

• Applicable Applications for anti-PTPN20B antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:300
• Immunogen: Synthetic peptide of human PTPN20B
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of K562 cell and Human testis tissue using PTPN20B Polyclonal Antibody at dilution of 1:200)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human cervical cancer using PTPN20B Polyclonal Antibody at dilution of 1:30)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human ovarian cancer using PTPN20B Polyclonal Antibody at dilution of 1:30)

Related Product Information for anti-PTPN20B antibody

The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

• NCBI GI #: 219521790
• NCBI GeneID: 26095
• Molecular Weight: 15,384 Da
• NCBI Official Full Name: PTPN20B protein
• NCBI Official Synonym Full Names: protein tyrosine phosphatase, non-receptor type 20B
• NCBI Official Symbol: PTPN20B
• NCBI Official Synonym Symbols: CT126; PTPN20A; hPTPN20; bA42B19.1; bA142I17.1
• NCBI Protein Information: tyrosine-protein phosphatase non-receptor type 20; cancer/testis antigen 126; protein tyrosine phosphatase, non-receptor type 20A
• UniProt Protein Name: Tyrosine-protein phosphatase non-receptor type 20
• UniProt Gene Name: PTPN20A
• UniProt Synonym Gene Names: hPTPN20
• UniProt Entry Name: PTN20_HUMAN

NCBI Description

The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Uniprot Description

PTPN20A: Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. 15 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA); EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 10q11.22

Cellular Component: microtubule; cytoplasm; microtubule organizing center; nucleus

Molecular Function: protein tyrosine phosphatase activity