Western Blot (WB)
(PTMA Antibody (N-term) (MBS9212204) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PTMA antibody detected the PTMA protein (arrow).)
Rabbit PTMA Polyclonal Antibody | anti-PTMA antibody
PTMA Antibody (N-term)
Gene Names
PTMA; TMSA
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Applications
Western Blot, ELISA, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PTMA; Polyclonal Antibody; PTMA Antibody (N-term); Prothymosin alpha; N-terminally processed; Thymosin alpha-1; TMSA; anti-PTMA antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PTMA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-31 amino acids from the N-terminal region of human PTMA.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
1-31
Sequence Length
110
Applicable Applications for anti-PTMA antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
IHC-P~~1:50~100
FC~~1:10~50
Function
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Cellular Location
Nucleus
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(PTMA Antibody (N-term) (MBS9212204) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PTMA antibody detected the PTMA protein (arrow).)
Western Blot (WB)
(PTMA Antibody (N-term) (MBS9212204) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PTMA antibody detected the PTMA protein (arrow).)
Immunohistochemistry (IHC)
(PTMA Antibody (N-term) (MBS9212204) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTMA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(PTMA Antibody (N-term) (MBS9212204) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTMA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(PTMA Antibody (N-term) (MBS9212204) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(PTMA Antibody (N-term) (MBS9212204) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-PTMA antibody
References
Qi, X., et al. Biochemistry 49(9):1923-1930(2010)
Skopeliti, M., et al. Mol. Immunol. 46(5):784-792(2009)
Pawlikowski, M., et al. Folia Histochem. Cytobiol. 47(4):559-562(2009)
Zakharova, N.I., et al. Mol. Biol. (Mosk.) 42(4):673-684(2008)
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Skopeliti, M., et al. Mol. Immunol. 46(5):784-792(2009)
Pawlikowski, M., et al. Folia Histochem. Cytobiol. 47(4):559-562(2009)
Zakharova, N.I., et al. Mol. Biol. (Mosk.) 42(4):673-684(2008)
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12203
NCBI Official Full Name
prothymosin alpha isoform 1
NCBI Official Synonym Full Names
prothymosin, alpha
NCBI Official Symbol
PTMA
NCBI Official Synonym Symbols
TMSA
NCBI Protein Information
prothymosin alpha
UniProt Protein Name
Prothymosin alpha
Protein Family
UniProt Gene Name
PTMA
UniProt Synonym Gene Names
TMSA
UniProt Entry Name
PTMA_HUMAN
Uniprot Description
PTMA: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. Belongs to the pro/parathymosin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Cell cycle regulation
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: transcription, DNA-dependent
Research Articles on PTMA
Similar Products
Product Notes
The PTMA ptma (Catalog #AAA9212204) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-31. The PTMA Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's PTMA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50. Researchers should empirically determine the suitability of the PTMA ptma for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTMA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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