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Western Blot (WB) (PTMA Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PTMA antibody detected the PTMA protein (arrow).)

Rabbit anti-Human PTMA Polyclonal Antibody | anti-PTMA antibody

PTMA, NT (PTMA, TMSA, Prothymosin alpha, Thymosin alpha-1) (Biotin)

Gene Names
PTMA; TMSA
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PTMA; Polyclonal Antibody; NT (PTMA; TMSA; Prothymosin alpha; Thymosin alpha-1) (Biotin); Thymosin alpha-1; anti-PTMA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-PTMA antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), ELISA (EIA)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
PTMA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-39 amino acids from the N-terminal region of human PTMA.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PTMA Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PTMA antibody detected the PTMA protein (arrow).)

Western Blot (WB) (PTMA Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PTMA antibody detected the PTMA protein (arrow).)

Immunohistochemistry (IHC)

(PTMA Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTMA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (PTMA Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTMA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(PTMA Antibody (N-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (PTMA Antibody (N-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-PTMA antibody
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Product Categories/Family for anti-PTMA antibody
References
Qi, X., et al. Biochemistry 49(9):1923-1930(2010). Skopeliti, M., et al. Mol. Immunol. 46(5):784-792(2009). Pawlikowski, M., et al. Folia Histochem. Cytobiol. 47(4):559-562(2009). Zakharova, N.I., et al. Mol. Biol. (Mosk.) 42(4):673-684(2008). Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,074 Da
NCBI Official Full Name
prothymosin alpha isoform 1
NCBI Official Synonym Full Names
prothymosin, alpha
NCBI Official Symbol
PTMA
NCBI Official Synonym Symbols
TMSA
NCBI Protein Information
prothymosin alpha; gene sequence 28; prothymosin alpha protein
UniProt Protein Name
Prothymosin alpha
Protein Family
UniProt Gene Name
PTMA
UniProt Synonym Gene Names
TMSA
UniProt Entry Name
PTMA_HUMAN

Uniprot Description

PTMA: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. Belongs to the pro/parathymosin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q37.1

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: transcription, DNA-dependent

Research Articles on PTMA

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Product Notes

The PTMA ptma (Catalog #AAA6338845) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTMA, NT (PTMA, TMSA, Prothymosin alpha, Thymosin alpha-1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTMA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), ELISA (EIA). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PTMA ptma for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTMA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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