SDS-Page
Prothymosin alpha Recombinant Protein | PTMA recombinant protein
Recombinant Human Prothymosin alpha protein
Gene Names
PTMA; TMSA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Prothymosin alpha; Recombinant Human Prothymosin alpha protein; PTMA recombinant protein
Host
E Coli
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
5-109
Sequence
AVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNANEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTKKQKTDED
Sequence Length
111
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-Page
SDS-Page
Related Product Information for PTMA recombinant protein
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Product Categories/Family for PTMA recombinant protein
References
The human prothymosin alpha gene is polymorphic and induced upon growth stimulation
evidence using a cloned cDNA.Eschenfeldt W.H., Berger S.L.Proc. Natl. Acad. Sci. U.S.A. 83:9403-9407(1986)
Molecular cloning of cDNA for human prothymosin alpha.Goodall G.J., Dominguez F., Horecker B.L.Proc. Natl. Acad. Sci. U.S.A. 83:8926-8928(1986)
Isolation and partial sequencing of the human prothymosin alpha gene family. Evidence against export of the gene products.Eschenfeldt W.H., Manrow R.E., Krug M.S., Berger S.L.J. Biol. Chem. 264:7546-7555(1989)
The expression of prothymosin alpha gene in T lymphocytes and leukemic lymphoid cells is tied to lymphocyte proliferation.Gomez-Marquez J., Segade F., Dosil M., Pichel J.G., Bustelo X.R., Freire M.J. Biol. Chem. 264:8451-8454(1989)
A novel prothymosin alpha cDNA from thymus.Li Z., Fan Q., Huang W., An L.
Prothymosin alpha gene in humans
organization of its promoter region and localization to chromosome 2.Szabo P., Panneerselvam C., Clinton M., Frangou-Lazaridis M., Weksler D., Whittington E., Macera M.J., Grzeschik K.H., Selvakumar A., Horecker B.L.Hum. Genet. 90:629-634(1993)
Human prothymosin alpha
amino acid sequence and immunologic properties.Pan L.X., Haritos A.A., Wideman J., Komiyama T., Chang M., Stein S., Salvin S.B., Horecker B.L.Arch. Biochem. Biophys. 250:197-201(1986)
Phosphorylation of human and bovine prothymosin alpha in vivo.Sburlati A.R., De La Rosa A., Batey D.W., Kurys G.L., Manrow R.E., Pannell L.K., Martin B.M., Sheeley D.M., Berger S.L.Biochemistry 32:4587-4596(1993)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.Cell 127:635-648(2006)
A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008)
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.Anal. Chem. 81:4493-4501(2009)
Large-scale proteomics analysis of the human kinome.Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G., Mann M., Daub H.Mol. Cell. Proteomics 8:1751-1764(2009)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.Sci. Signal. 2:RA46-RA46(2009)
Lysine acetylation targets protein complexes and co-regulates major cellular functions.Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.Science 325:834-840(2009)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.Sci. Signal. 3:RA3-RA3(2010)
Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.Sci. Signal. 4:RS3-RS3(2011)
Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012)
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012)
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
NMR structure of human thymosin alpha-1.Elizondo-Riojas M.A., Chamow S.M., Tuthill C.W., Gorenstein D.G., Volk D.E.Biochem. Biophys. Res. Commun. 416:356-361(2011)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38.9kD
NCBI Official Full Name
prothymosin alpha isoform 1
NCBI Official Synonym Full Names
prothymosin, alpha
NCBI Official Symbol
PTMA
NCBI Official Synonym Symbols
TMSA
NCBI Protein Information
prothymosin alpha
UniProt Protein Name
Prothymosin alpha
Protein Family
UniProt Gene Name
PTMA
UniProt Synonym Gene Names
TMSA
UniProt Entry Name
PTMA_HUMAN
Uniprot Description
PTMA: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. Belongs to the pro/parathymosin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: transcription, DNA-dependent
Research Articles on PTMA
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Product Notes
The PTMA ptma (Catalog #AAA1265143) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 5-109. The amino acid sequence is listed below: AVDTSSEITT KDLKEKKEVV EEAENGRDAP ANGNANEENG EQEADNEVDE EEEEGGEEEE EEEEGDGEEE DGDEDEEAES ATGKRAAEDD EDDDVDTKKQ KTDED. It is sometimes possible for the material contained within the vial of "Prothymosin alpha, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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