Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human PTGR1/LTB4DH Polyclonal Antibody | anti-PTGR1/LTB4DH antibody
Anti-PTGR1/LTB4DH Antibody (aa75-124)
Gene Names
PTGR1; PGR1; ZADH3; LTB4DH
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
PTGR1/LTB4DH; Polyclonal Antibody; Anti-PTGR1/LTB4DH Antibody (aa75-124); Rabbit Polyclonal to Human PTGR1/LTB4DH; PTGR1; PGR1; ZADH3; PRG-1; LTB4DH; Prostaglandin reductase 1; anti-PTGR1/LTB4DH antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
PTGR1 Antibody detects endogenous levels of total PTGR1 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Sequence Length
329
Applicable Applications for anti-PTGR1/LTB4DH antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:5000
IHC-P: 1:50
WB: 1:500-1:1000
IHC-P: 1:50
WB: 1:500-1:1000
Immunogen
Synthetic peptide from human PTGR1 (aa75-124).
Conjugation
Unconjugated
Epitope
aa75-124
Preparation and Storage
Store at -20 degree C for up to one year.
Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot of extracts from HT-29 cells, using PTGR1 Antibody. The lane on the right is treated with the synthesized peptide.)
Western Blot (WB)
(Western blot of extracts from HT-29 cells, using PTGR1 Antibody. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-PTGR1/LTB4DH antibody
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotrieneB4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotrieneB4.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,895 Da
NCBI Official Full Name
prostaglandin reductase 1 isoform 1
NCBI Official Synonym Full Names
prostaglandin reductase 1
NCBI Official Symbol
PTGR1
NCBI Official Synonym Symbols
PGR1; ZADH3; LTB4DH
NCBI Protein Information
prostaglandin reductase 1
UniProt Protein Name
Prostaglandin reductase 1
UniProt Gene Name
PTGR1
UniProt Synonym Gene Names
LTB4DH; PRG-1
NCBI Description
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Uniprot Description
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
Research Articles on PTGR1/LTB4DH
Similar Products
Product Notes
The PTGR1/LTB4DH ptgr1 (Catalog #AAA2401559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PTGR1/LTB4DH Antibody (aa75-124) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTGR1/LTB4DH can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:5000 IHC-P: 1:50 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the PTGR1/LTB4DH ptgr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGR1/LTB4DH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
