Rabbit anti-Human NOVA1 Polyclonal Antibody | anti-NOVA1 antibody

NOVA1 (Neuro-oncological Ventral Antigen 1, Nova-1) (PE)

Cat. Num. AAA6429454

• Gene Names: NOVA1; Nova-1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: NOVA1; Polyclonal Antibody; NOVA1 (Neuro-oncological Ventral Antigen 1; Nova-1) (PE); anti-NOVA1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human NOVA1.
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-NOVA1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide corresponding to human NOVA1.
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of HeLa cell line, using NOVA1 antibody.)

Product Categories/Family for anti-NOVA1 antibody

Antibodies; Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 56549653
• NCBI GeneID: 4857
• NCBI Accession #: NP_002506.2
• NCBI GenBank Nucleotide #: NM_002515.2
• UniProt Accession #: P51513; Q6B004; A8K0S4; A8K4Q7; D3DS81; D3DS82
• Molecular Weight: 49,253 Da
• NCBI Official Full Name: RNA-binding protein Nova-1 isoform 1
• NCBI Official Synonym Full Names: neuro-oncological ventral antigen 1
• NCBI Official Symbol: NOVA1
• NCBI Official Synonym Symbols: Nova-1
• NCBI Protein Information: RNA-binding protein Nova-1; paraneoplastic Ri antigen; onconeural ventral antigen 1; ventral neuron-specific protein 1
• UniProt Protein Name: RNA-binding protein Nova-1
• Protein Family: RNA-binding protein
• UniProt Gene Name: NOVA1
• UniProt Entry Name: NOVA1_HUMAN

NCBI Description

This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

NOVA1: May regulate RNA splicing or metabolism in a specific subset of developing neurons. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 14q

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus

Molecular Function: mRNA binding; RNA binding

Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; synaptic transmission; regulation of RNA metabolic process; RNA splicing; locomotory behavior