Rabbit anti-Human PTGER2 Polyclonal Antibody | anti-PTGER2 antibody
PTGER2, ID (Prostanoid EP2 Receptor, Prostaglandin E2 Receptor EP2 Subtype, PGE2 Receptor EP2 Subtype, PGE Receptor EP2 Subtype) (APC)
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of PTGER2 Antibody (Center) in HL-60 cell line lysates (35ug/lane).PTGER2 (arrow) was detected using the purified Pab.)
Testing Data
(PTGER2 Antibody (Center) FC analysis of ZR-75-1 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]
Uniprot Description
PTGER2: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 14q22
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: prostaglandin E receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide; G-protein signaling, adenylate cyclase activating pathway; regulation of cell proliferation
Disease: Asthma, Nasal Polyps, And Aspirin Intolerance
Research Articles on PTGER2
Similar Products
Product Notes
The PTGER2 ptger2 (Catalog #AAA6494755) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTGER2, ID (Prostanoid EP2 Receptor, Prostaglandin E2 Receptor EP2 Subtype, PGE2 Receptor EP2 Subtype, PGE Receptor EP2 Subtype) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTGER2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-1:500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PTGER2 ptger2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGER2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.