Western Blot (WB)
(PTDSS1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PTDSS1 antibody detected the PTDSS1 protein (arrow).)
Rabbit anti-Human PTDSS1 Polyclonal Antibody | anti-PTDSS1 antibody
PTDSS1, CT (PTDSS1, KIAA0024, PSSA, Phosphatidylserine synthase 1, Serine-exchange enzyme I)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(PTDSS1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PTDSS1 antibody detected the PTDSS1 protein (arrow).)
Western Blot (WB)
(PTDSS1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PTDSS1 antibody detected the PTDSS1 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).[supplied by OMIM, May 2009]
Uniprot Description
PTDSS1: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. Belongs to the phosphatidyl serine synthase family.
Protein type: Membrane protein, multi-pass; Mitochondrial; Transferase; EC 2.7.8.29; Lipid Metabolism - glycerophospholipid; Membrane protein, integral
Chromosomal Location of Human Ortholog: 8q22
Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane
Molecular Function: transferase activity
Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylserine biosynthetic process
Disease: Lenz-majewski Hyperostotic Dwarfism
Research Articles on PTDSS1
Similar Products
Product Notes
The PTDSS1 ptdss1 (Catalog #AAA6002694) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTDSS1, CT (PTDSS1, KIAA0024, PSSA, Phosphatidylserine synthase 1, Serine-exchange enzyme I) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTDSS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the PTDSS1 ptdss1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTDSS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
