Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using PSMD13 Antibody.)
Rabbit PSMD13 Polyclonal Antibody | anti-PSMD13 antibody
PSMD13 Polyclonal Antibody
IHC: 1:50-1:200
IF: 1:50-1:200
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using PSMD13 Antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using PSMD13 Antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat brain using PSMD13 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat brain using PSMD13 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human esophagus using PSMD13 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human esophagus using PSMD13 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using PSMD13 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using PSMD13 antibody.)
NCBI and Uniprot Product Information
Observed: 45kDa
NCBI Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Research Articles on PSMD13
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Product Notes
The PSMD13 psmd13 (Catalog #AAA2554578) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PSMD13 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PSMD13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the PSMD13 psmd13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSMD13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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