Immunohistochemistry (IHC)
(Immunochemical staining of human PSMD1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human PSMD1 Polyclonal Antibody | anti-PSMD1 antibody
Anti-PSMD1 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
PSMD1; Polyclonal Antibody; Anti-PSMD1 Antibody; Rabbit Polyclonal; PSMD1 Antibody; Rabbit PAb; Antigen Affinity Purified; proteasome 26S subunit; non-ATPase 1; Anti-P112 Antibody; Anti-Rpn2 Antibody; Anti-S1 Antibody; anti-PSMD1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human PSMD1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-PSMD1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human PSMD1 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human PSMD1 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human PSMD1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human PSMD1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-PSMD1 antibody
PSMD1 (Proteasome 26S Subunit, Non-ATPase 1) is a Protein Coding gene. The PSMD1 gene, located on 2q37.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, and mouse, etc. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively, spliced transcript variants have been found for this gene. PSMD1is widely expressed in the brain, appendix, and other tissues. Diseases associated with PSMD1 include Blepharochalasis and Cystic Fibrosis. The related pathways of PSMD1 are Regulation of activated PAK-2p34 by proteasome-mediated degradation and Antigen processing-Cross presentation. 232 organisms have orthologs with the human gene PSMD1.
References
Ryu H, et al. (2014) Sumoylation of psmd1 controls adrm1 interaction with the proteasome. Cell Rep 7 (6): 1842-1848.Lu X, et al. (2020) An extended conformation for k48 ubiquitin chains revealed by the hrpn2:Rpn13:K48-diubiquitin structure. Structure 28 (5): 495-506.e493.Ahmad S, et al. (2020) Association of intronic polymorphisms (rs1549339, rs13402242) and mrna expression variations in psmd1 gene in arsenic-exposed workers. Environ Sci Pollut Res Int 27 (10): 11425-11437.
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Product Notes
The PSMD1 (Catalog #AAA8108920) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PSMD1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSMD1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the PSMD1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSMD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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