Rabbit PSGR Polyclonal Antibody | anti-PSGR antibody

PSGR (F237) Polyclonal Antibody

Cat. Num. AAA3003100

• Gene Names: OR51E2; PSGR; HPRAJ; OR52A2; OR51E3P
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: PSGR; Polyclonal Antibody; PSGR (F237) Polyclonal Antibody; Olfactory receptor 51E2; HPRAJ; Olfactory receptor OR11-16; Prostate-specific G-protein coupled receptor; OR51E2; anti-PSGR antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: PSGR (F237) polyclonal antibody detects endogenous levels of PSGR protein
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 320

• Applicable Applications for anti-PSGR antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 202-250 of Human PSGR.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of PSGR (F237) polyclonal antibody at 1:500 dilutionLane1:Jurkat whole cell lysateLane2:Raw264. 7 whole cell lysateLane3:PC12 whole cell lysate)

Western Blot (WB)

(Western Blot (WB) analysis of PSGR (F237) pAb at 1:500 dilutionLane1:PC3 whole cell lysate (40ug) Lane2:L02 whole cell lysate (40ug) Lane3:AML-12 whole cell lysate (40ug) Lane4:H9C2 whole cell lysate (40ug))

Related Product Information for anti-PSGR antibody

PSGR (prostate-specific G-protein coupled receptor), also known as OR51E2 (olfactory receptor 51E2), is a 320 amino acid multi-pass membrane protein that belongs to the olfactory receptor subfamily of G-protein coupled receptors. Expressed exclusively in prostate tissue and upregulated in prostate cancer, PSGR functions as an odorant receptor that binds odorant molecules and triggers the perception of smell.

NCBI and Uniprot Product Information

• NCBI GI #: 13540539
• NCBI GeneID: 81285
• NCBI Accession #: NP_110401.1
• NCBI GenBank Nucleotide #: NP_110401.1
• UniProt Accession #: Q9H255
• Molecular Weight: ~ 35kDa
• NCBI Official Full Name: olfactory receptor 51E2
• NCBI Official Synonym Full Names: olfactory receptor family 51 subfamily E member 2
• NCBI Official Symbol: OR51E2
• NCBI Official Synonym Symbols: PSGR; HPRAJ; OR52A2; OR51E3P
• NCBI Protein Information: olfactory receptor 51E2
• UniProt Protein Name: Olfactory receptor 51E2
• UniProt Gene Name: OR51E2
• UniProt Synonym Gene Names: PSGR
• UniProt Entry Name: O51E2_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR51E2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; olfactory receptor activity; steroid hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell; steroid hormone mediated signaling; positive regulation of blood pressure