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Western Blot (WB) (Western blot analysis of PSG7 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). PSG7 (arrow) was detected using the purified Pab.)

Rabbit anti-Human PSG7 Polyclonal Antibody | anti-PSG7 antibody

PSG7 Antibody (C-term)

Gene Names
PSG7; PSG1; PSGGA; PSBG-7
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PSG7; Polyclonal Antibody; PSG7 Antibody (C-term); Putative pregnancy-specific beta-1-glycoprotein 7; PS-beta-G-7; PSBG-7; Pregnancy-specific glycoprotein 7; anti-PSG7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PSG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-293 amino acids from the C-terminal region of human PSG7.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
265-293
Sequence Length
419
Applicable Applications for anti-PSG7 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of PSG7 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). PSG7 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of PSG7 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). PSG7 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(PSG7 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PSG7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (PSG7 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PSG7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(PSG7 Antibody (C-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (PSG7 Antibody (C-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-PSG7 antibody
PSG7 is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene.
References
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Beauchemin, N., et al. Exp. Cell Res. 252(2):243-249(1999)
Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47001
NCBI Official Full Name
putative pregnancy-specific beta-1-glycoprotein 7 isoform 1
NCBI Official Synonym Full Names
pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
NCBI Official Symbol
PSG7
NCBI Official Synonym Symbols
PSG1; PSGGA; PSBG-7
NCBI Protein Information
putative pregnancy-specific beta-1-glycoprotein 7
UniProt Protein Name
Putative pregnancy-specific beta-1-glycoprotein 7
UniProt Gene Name
PSG7
UniProt Synonym Gene Names
PS-beta-G-7; PSBG-7; Pregnancy-specific glycoprotein 7
UniProt Entry Name
PSG7_HUMAN

NCBI Description

This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Uniprot Description

PSG7: a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular region

Biological Process: female pregnancy

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Product Notes

The PSG7 psg7 (Catalog #AAA9203718) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 265-293. The PSG7 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSG7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the PSG7 psg7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSG7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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