Rabbit anti-Human PSAPL1 Polyclonal Antibody | anti-PSAPL1 antibody

PSAPL1, NT (PSAPL1, Proactivator polypeptide-like 1, Saposin A-like, Saposin B-Val-like, Saposin B-like, Saposin C-like, Saposin D-like)

Cat. Num. AAA649512

• Reactivity: Human
• Applications: ELISA, Western Blot, Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: PSAPL1; Polyclonal Antibody; NT (PSAPL1; Proactivator polypeptide-like 1; Saposin A-like; Saposin B-Val-like; Saposin B-like; Saposin C-like; Saposin D-like); Anti -PSAPL1; anti-PSAPL1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-PSAPL1 antibody: ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Western Blot, Flow Cytometry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Flow Cytometry: 1:10-50
• Immunogen: PSAPL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the N-terminal region of human PSAPL1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PSAPL1 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PSAPL1 antibody detected the PSAPL1 protein (arrow).)

Flow Cytometry (FC/FACS)

(PSAPL1 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-PSAPL1 antibody

PSAPL1 may activate the lysosomal degradation of sphingolipids (By similarity).

Product Categories/Family for anti-PSAPL1 antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 145977198
• NCBI GeneID: 768239
• NCBI Accession #: NP_001078851.1
• NCBI GenBank Nucleotide #: NM_001085382.1
• UniProt Accession #: Q6NUJ1; Q8N7T4; A0A184
• Molecular Weight: 56,627 Da
• NCBI Official Full Name: proactivator polypeptide-like 1 preproprotein
• NCBI Official Synonym Full Names: prosaposin-like 1 (gene/pseudogene)
• NCBI Official Symbol: PSAPL1
• NCBI Protein Information: proactivator polypeptide-like 1; prosaposin-like protein 1
• UniProt Protein Name: Proactivator polypeptide-like 1
• Protein Family: Proactivator polypeptide
• UniProt Gene Name: PSAPL1
• UniProt Entry Name: SAPL1_HUMAN

NCBI Description

This gene encodes a protein that is related to the glycoprotein prosaposin. Based on sequence similarity between the encoded protein and prosaposin, it is predicted that the encoded protein is a preproprotein that is proteolytically processed to generate multiple protein products. These predicted products include saposins A-like, B-like, C-like, and D-like, which may play a role in the lysosomal degradation of sphingolipids. [provided by RefSeq, Jul 2015]

Uniprot Description

Function: May activate the lysosomal degradation of sphingolipids

By similarity.

Subcellular location: Secreted

Potential.

Sequence similarities: Contains 2 saposin A-type domains.Contains 4 saposin B-type domains.

Sequence caution: The sequence AAH68579.1 differs from that shown. Reason: Erroneous initiation. The sequence BAC05143.1 differs from that shown. Reason: Erroneous termination at position 510. Translated as Trp.