Western Blot (WB)
(PRRX2 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PRRX2 antibody detected the PRRX2 protein (arrow).)
Rabbit anti-Mouse PRRX2 Polyclonal Antibody | anti-PRRX2 antibody
PRRX2 Antibody (C-term)
Western Blot (WB)
(PRRX2 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PRRX2 antibody detected the PRRX2 protein (arrow).)
Western Blot (WB)
(PRRX2 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PRRX2 antibody detected the PRRX2 protein (arrow).)
member of the paired family of homeobox proteins. Expression is
localized to proliferating fetal fibroblasts and the developing
dermal layer, with downregulated expression in adult skin.
Increases in expression of this gene during fetal but not adult
wound healing suggest a possible role in mechanisms that control
mammalian dermal regeneration and prevent formation of scar
response to wounding. The expression patterns provide evidence
consistent with a role in fetal skin development and a possible
role in cellular proliferation.
Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) :
Tokutomi, Y., et al. Biochem. Biophys. Res. Commun. 364(4):822-830(2007)
Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)
Gervais, C., et al. Leukemia 19(1):145-148(2005)
NCBI and Uniprot Product Information
NCBI Description
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]
Uniprot Description
PRRX2: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. Belongs to the paired homeobox family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 9q34.1
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding; transcription factor activity
Biological Process: inner ear morphogenesis; regulation of transcription, DNA-dependent; cartilage development; positive regulation of mesenchymal cell proliferation; artery morphogenesis; positive regulation of smoothened signaling pathway; middle ear morphogenesis; embryonic cranial skeleton morphogenesis; embryonic limb morphogenesis
Research Articles on PRRX2
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Product Notes
The PRRX2 prrx2 (Catalog #AAA9213292) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 223-250. The PRRX2 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PRRX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PRRX2 prrx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRRX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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