Western Blot (WB)
(Western Blot: Sample: Human A431 Cells.)
Rabbit anti-Human Prostaglandin Endoperoxide Synthase 1 (PTGS1) Polyclonal Antibody | anti-PTGS1 antibody
Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 1 (PTGS1)
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Human A431 Cells.)
Western Blot (WB)
(Western Blot: Sample: Human A431 Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PTGS1, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PTGS1, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Rectum Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Rectum Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue.)
NCBI and Uniprot Product Information
NCBI Description
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Description
COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.14.99.1; Lipid Metabolism - arachidonic acid; Oxidoreductase
Chromosomal Location of Human Ortholog: 9q33.2
Cellular Component: cytoplasm; endoplasmic reticulum membrane; Golgi apparatus; intracellular membrane-bound organelle; nucleus; photoreceptor outer segment
Molecular Function: dioxygenase activity; heme binding; metal ion binding; peroxidase activity; prostaglandin-endoperoxide synthase activity
Biological Process: cyclooxygenase pathway; inflammatory response; lipid metabolic process; prostaglandin biosynthetic process; regulation of blood pressure; regulation of cell proliferation; response to oxidative stress; xenobiotic metabolic process
Research Articles on PTGS1
Similar Products
Product Notes
The PTGS1 ptgs1 (Catalog #AAA2007299) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 1 (PTGS1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Prostaglandin Endoperoxide Synthase 1 (PTGS1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the PTGS1 ptgs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prostaglandin Endoperoxide Synthase 1 (PTGS1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
