Western Blot (WB)
(Western blot analysis of recombinant Human PEN2 protein. Primary antibody: 2 ug/ml Rabbit Anti-PEN2 Polyclonal Antibody . The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.)
Rabbit Presenilin Enhancer 2 Polyclonal Antibody | anti-Psenen antibody
Presenilin Enhancer 2 (PEN2, MDS033)
Gene Names
Psenen; ACYPI006208
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Presenilin Enhancer 2; Polyclonal Antibody; Presenilin Enhancer 2 (PEN2; MDS033); Anti -Presenilin Enhancer 2 (PEN2; anti-Psenen antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PEN2.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 30% glycerol.
Applicable Applications for anti-Psenen antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.05-0.2ug/ml
Western Blot: 1-2ug/ml
Dilution: ELISA: 0.05-0.2ug/ml
Western Blot: 1-2ug/ml
Immunogen
Synthetic peptide (KLH-conjugated) corresponding to human PEN2
Preparation and Storage
For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Western Blot (WB)
(Western blot analysis of recombinant Human PEN2 protein. Primary antibody: 2 ug/ml Rabbit Anti-PEN2 Polyclonal Antibody . The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.)
Western Blot (WB)
(Western blot analysis of recombinant Human PEN2 protein. Primary antibody: 2 ug/ml Rabbit Anti-PEN2 Polyclonal Antibody . The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.)
Related Product Information for anti-Psenen antibody
Presenilin enhancer protein 2 (PEN2) is a 101-amino acid protein that traverses the membrane twice and it is the regulatory component of the multimeric gamma-secretase complex which also consists of presenilin, APH-1 and Nicastrin. The gamma-secretase complex catalyzes the cleavage of a number of integral membrane proteins including beta-amyloid precursor protein (APP), Notch protein, Erb4 and E-cadherin. The gamma-secretase complex cleaves the APP yielding amyloid beta peptide, which is the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease. In addition, PEN2 is required for end proteolysis of presenilin and activation of the gamma-secretase.
Product Categories/Family for anti-Psenen antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
presenilin enhancer 2
NCBI Official Synonym Full Names
presenilin enhancer 2
NCBI Official Symbol
Psenen
NCBI Official Synonym Symbols
ACYPI006208
NCBI Protein Information
presenilin enhancer 2
Protein Family
Similar Products
Product Notes
The Psenen (Catalog #AAA622075) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Presenilin Enhancer 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 0.05-0.2ug/ml Western Blot: 1-2ug/ml. Researchers should empirically determine the suitability of the Psenen for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Presenilin Enhancer 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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