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Western Blot (WB) (PRDX3 rabbit polyclonal antibody. Western Blot analysis of PRDX3 expression in mouse spleen.)

Rabbit anti-Human, Mouse PRDX3 Polyclonal Antibody | anti-PRDX3 antibody

PRDX3 (Thioredoxin-dependent Peroxide Reductase, Mitochondrial, Antioxidant Protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 Homolog, AOP1, MER5, MGC104387, MGC24293, PRO1748) APC

Gene Names
PRDX3; AOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PRDX3; Polyclonal Antibody; PRDX3 (Thioredoxin-dependent Peroxide Reductase; Mitochondrial; Antioxidant Protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 Homolog; AOP1; MER5; MGC104387; MGC24293; PRO1748) APC; anti-PRDX3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PRDX3. Species Crossreactivity: mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-PRDX3 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human PRDX3, aa1-256 (NP_006784.1).
Immunogen Sequence
MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
Conjugate
APC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PRDX3 rabbit polyclonal antibody. Western Blot analysis of PRDX3 expression in mouse spleen.)

Western Blot (WB) (PRDX3 rabbit polyclonal antibody. Western Blot analysis of PRDX3 expression in mouse spleen.)

Western Blot (WB)

(Western Blot analysis of PRDX3 expression in transfected 293T cell line by PRDX3 polyclonal antibody. Lane 1: PRDX3 transfected lysate (27.7kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of PRDX3 expression in transfected 293T cell line by PRDX3 polyclonal antibody. Lane 1: PRDX3 transfected lysate (27.7kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-PRDX3 antibody
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Product Categories/Family for anti-PRDX3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
256
NCBI Official Full Name
thioredoxin-dependent peroxide reductase, mitochondrial isoform a
NCBI Official Synonym Full Names
peroxiredoxin 3
NCBI Official Symbol
PRDX3
NCBI Official Synonym Symbols
AOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III
NCBI Protein Information
thioredoxin-dependent peroxide reductase, mitochondrial; peroxiredoxin-3; peroxiredoxin III; protein MER5 homolog; antioxidant protein 1
UniProt Protein Name
Thioredoxin-dependent peroxide reductase, mitochondrial
UniProt Gene Name
PRDX3
UniProt Synonym Gene Names
AOP1; AOP-1; Prx-III
UniProt Entry Name
PRDX3_HUMAN

Uniprot Description

PRDX3: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Belongs to the AhpC/TSA family.

Protein type: Oxidoreductase; EC 1.11.1.15

Chromosomal Location of Human Ortholog: 10q25-q26

Cellular Component: mitochondrion; mitochondrial matrix; cytoplasm; early endosome; IkappaB kinase complex; cytosol

Molecular Function: protein C-terminus binding; identical protein binding; protein binding; thioredoxin peroxidase activity; caspase inhibitor activity; alkyl hydroperoxide reductase activity; kinase binding; protein kinase binding

Biological Process: negative regulation of kinase activity; mitochondrion organization and biogenesis; response to lipopolysaccharide; negative regulation of caspase activity; activation of NF-kappaB transcription factor; response to reactive oxygen species; peptidyl-cysteine oxidation; response to hydrogen peroxide; regulation of mitochondrial membrane potential; hydrogen peroxide catabolic process; positive regulation of cell proliferation; myeloid cell differentiation; response to oxidative stress; negative regulation of apoptosis; maternal placenta development

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Product Notes

The PRDX3 prdx3 (Catalog #AAA6390561) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRDX3 (Thioredoxin-dependent Peroxide Reductase, Mitochondrial, Antioxidant Protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 Homolog, AOP1, MER5, MGC104387, MGC24293, PRO1748) APC reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PRDX3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PRDX3 prdx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRDX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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