Rabbit PPP3CC Polyclonal Antibody | anti-PPP3CC antibody

PPP3CC Rabbit Polyclonal

Cat. Num. AAA7602962

• Gene Names: PPP3CC; CNA3; CALNA3; PP2Bgamma
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: PPP3CC; Polyclonal Antibody; PPP3CC Rabbit Polyclonal; anti-PPP3CC antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 418

• Applicable Applications for anti-PPP3CC antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(mouse testis tissue were subjected to SDS PAGE followed by western blot with MBS7602962 (PPP3CC antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 1034660833
• NCBI GeneID: 5533
• NCBI Accession #: XP_016869100.1
• NCBI GenBank Nucleotide #: XM_017013611.1
• Molecular Weight: 59,262 Da
• NCBI Official Full Name: serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X2
• NCBI Official Synonym Full Names: protein phosphatase 3 catalytic subunit gamma
• NCBI Official Symbol: PPP3CC
• NCBI Official Synonym Symbols: CNA3; CALNA3; PP2Bgamma
• NCBI Protein Information: serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
• UniProt Protein Name: Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
• Protein Family: Serine/threonine-protein phosphatase
• UniProt Gene Name: PPP3CC
• UniProt Synonym Gene Names: CALNA3; CNA3
• UniProt Entry Name: PP2BC_HUMAN

NCBI Description

Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Uniprot Description

PPP3CC: a calmodulin-dependent Ser/Thr phosphatase also known as calcineurin A gamma. Involved in a wide range of biologic activities, acting as a Ca(2 )-dependent modifier of phosphorylation status. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: cytosol; mitochondrion

Molecular Function: calmodulin binding; metal ion binding; phosphoprotein phosphatase activity; protein binding

Biological Process: brain development; protein amino acid dephosphorylation