Rabbit anti-Human PPP1R3C Polyclonal Antibody | anti-PPP1R3C antibody

PPP1R3C (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 3C, PPP1R5) (Biotin)

Cat. Num. AAA6451434

• Gene Names: PPP1R3C; PTG; PPP1R5
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified
• Synonyms: PPP1R3C; Polyclonal Antibody; PPP1R3C (Protein Phosphatase 1; Regulatory (Inhibitor) Subunit 3C; PPP1R5) (Biotin); Protein Phosphatase 1; PPP1R5; anti-PPP1R3C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PPP1R3C.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 317

• Applicable Applications for anti-PPP1R3C antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: PPP1R3C (AAH12625.1, 1aa-317aa) full-length human protein.
• Immunogen Sequence: MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of PPP1R3C expression in transfected 293T cell line by PPP1R3C MaxPab polyclonal antibody.Lane 1: PPP1R3C transfected lysate(34.98 KDa).Lane 2: Non-transfected lysate.)

Western Blot (WB)

(PPP1R3C MaxPab rabbit polyclonal antibody. Western Blot analysis of PPP1R3C expression in mouse kidney.)

Related Product Information for anti-PPP1R3C antibody

Protein phosphatase-1 (PP1; see MIM 176875) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits PPP1R3 (MIM 600917) and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8; MIM 602636).[supplied by OMIM]

Product Categories/Family for anti-PPP1R3C antibody

Antibodies; Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 15214995
• NCBI GeneID: 5507
• NCBI Official Full Name: Protein phosphatase 1, regulatory (inhibitor) subunit 3C
• NCBI Official Synonym Full Names: protein phosphatase 1 regulatory subunit 3C
• NCBI Official Symbol: PPP1R3C
• NCBI Official Synonym Symbols: PTG; PPP1R5
• NCBI Protein Information: protein phosphatase 1 regulatory subunit 3C
• Protein Family: Protein phosphatase 1 regulatory

NCBI Description

This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016]